Results 31 to 40 of about 530,775 (302)

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Assessing the complementarity and tradeoffs of climate smart agriculture adoption in northwestern Ethiopia

Discover Applied Sciences
Despite being highly dependent on erratic rainfall and frequently affected by drought and low productivity, agriculture remains the dominant economic activity in Ethiopia. The use of Climate-Smart Agriculture technologies can improve farming productivity,
Habtamu Mossie, Silabat Enyew, Melese Gezie, Zsuzsanna Bacsi   +3 more
doaj   +1 more source

Ensayo sobre fundamentos propios de los sistemas jurídicos: Hart, Dworkin, Ihering y Puchta [PDF]

, 2014
Lo que vale debe ser. No es un deber hacer, sino la simple enunciación de que lo valioso debe ser. Un deber hacer es igual a la perfección, a lo legítimo, porque el deber hacer supone la existencia de un valor; que ese deber ser, sea un ideal del mismo.
Domingo Centeno, Miguela
core   +1 more source

Evaluating the African arid corridor hypothesis: A meta‐analysis including the phylogenetic and biogeographical history of Sesamothamnus

American Journal of Botany, EarlyView.
Abstract Premise We examined the African arid corridor (AAC) disjunction pattern of vascular plants between northeastern and southwestern Africa in the context of geological and climatic events since the late Miocene. We developed a phylogenetic and biogeographical framework for the arid‐adapted genus Sesamothamnus (Pedaliaceae), a classic example of ...
John G. Zaborsky, Jeffrey P. Rose, Ricardo Kriebel, Bryan T. Drew, Emily Moriarty Lemmon, Alan R. Lemmon, Kenneth J. Sytsma   +6 more
wiley   +1 more source

The Homozygous p.(Arg215Ter) Variant in XRCC2 Is Associated With Atypical Fanconi Anemia Without Major Hematological Abnormalities in Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Fanconi Anemia (FA) is the most frequent inherited bone marrow failure syndrome. A role for the XRCC2 gene in FA was suspected in 2012 and confirmed in 2016, but only two affected individuals have been described thus far, and no long‐term follow‐up is available.
Sabina Cenciarelli, Giulia Bruna Marchetti, Maria Iascone, Maria Grazia Patricelli, Sara Giangiobbe, Gabriella Cinzia Pozzobon, Miriam Nella Savini, Fabio Giglio, Alessandro Aiuti, Paola Carrera, Francesca Ferrua, Angela Peron   +11 more
wiley   +1 more source

La noción de "alma bella" en el pensamiento de Hölderlin de Hegel

Humanidades, 2017
Varios comentaristas sostienen que el pensamiento de Friedrich Hölderlin es un ejemplo de la concepción hegeliana de «alma bella». En el presente artículo, se demostrará que la figura del Espíritu antes mencionada tiene fundamentos ontológicos que ...
Carlos Alfaro
doaj   +1 more source

Nano‐Gs‐Protein Peptidomimetika: Rationales Design von Peptiden, die vom C‐Terminus von Gα abgeleitet sind und Schlüsselkomponenten der Gs‐β2AR‐Wechselwirkungen nachahmen

Angewandte Chemie, EarlyView.
G Protein‐gekoppelte Rezeptoren (GPCRs) sind wichtige therapeutische Zielstrukturen. Die Modulation der GPCR‐Aktivität über intrazelluläre Bindungsstellen gewinnt zunehmend an Bedeutung. Ein strukturell und computergestützter Ansatz ermöglichte die Entwicklung kleiner, vom G Protein abgeleiteter Peptidomimetika, die gezielt an die intrazelluläre ...
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Propuesta de protocolo para la identificación y evaluación de barreras arquitectònicas en situaciones de evacuación, en edificios de uso público [PDF]

, 2012
Para el desarrollo del trabajo hemos elaborado un protocolo con la finalidad de poder ser utilizado como checklist. Éste, está destinado para utilizarse en edificios de uso público, y ayudar a identificar las barreras arquitectónicas de manera rápida y
García Toro, Mireia, Labrador Deber, Erica   +1 more
core  

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

La informacion privilegiada en el mercado de valores chileno. Figuras infraccionales contempladas en el articulo 165 de la ley 18.045. [PDF]

, 2008
44 p.El presente trabajo comienza dando una visión general de la institución de la información privilegiada y la visión doctrinaria y jurisprudencial al respecto.
Ruz Lartiga, Gonzalo (Prof. Guia), Silva Carrasco, Ivan   +1 more
core