Results 41 to 50 of about 102,489 (297)

Negative Pressure Wound Therapy with Instillation and Dwell Time using Vacuum Assisted Closure Novel Foam Dressing as a Limb Salvaging Strategy in a Complex Diabetic Plantar Ulcer: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Diabetic foot ulcers remain a major cause of morbidity and lower limb amputation worldwide, particularly in patients with neuropathy, ischaemia, and infection where conventional wound care often fails.
Bhavyal Sinha, R Manimaran, K Kanchana Batra   +2 more
doaj   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Modern Perspectives on Fournier’s Gangrene: A Narrative Review of Surgical Advances, and Adjunctive Therapies [PDF]

Journal of Clinical and Diagnostic Research
Fournier’s Gangrene (FG) is a rare but rapidly progressive necrotising fasciitis of the perineal, genital, and perianal areas, more commonly occurring in older males with comorbidities such as diabetes mellitus and immunosuppression.
Ayush Gandhi, Pooja Batra, Bhagyesh Sapkale   +2 more
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Managing Rhino-cerebral Mucormycosis: Institutional Experience

Bengal Journal of Otolaryngology and Head Neck Surgery, 2019
Introduction Rhinocerebral mucormycosis is a rapidly progressive life threatening opportunistic fungal disease and usually occurs in individuals with weakened immune system. It is caused by filamentous fungi of Mucorales from class Mucormycotina.
Kalpesh Patel, Abhishek Gugliani, Dhwani Mehta   +2 more
doaj  

Debridement for surgical wounds [PDF]

Cochrane Database of Systematic Reviews, 2008
Surgical wounds that become infected are often debrided because clinicians believe that removal of this necrotic or infected tissue will expedite wound healing. There are numerous methods available but no consensus on which one is most effective for surgical wounds.To determine the effect of different methods of debridement on the rate of debridement ...
Smith, Fiona, Dryburgh, Nancy, Donaldson, JH, Mitchell, Melloney   +3 more
openaire   +5 more sources

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Femtosecond‐Laser Nanocavitation Regenerates SERS‐Active Plasmonic Nanogaps for Longitudinal Molecular Sensing at Biointerfaces

Advanced Science, EarlyView.
A regenerative molecular sensing platform that co‐localizes surface‐enhanced Raman spectroscopy (SERS) sensing and nanocavitation‐based actuation. Femtosecond‐laser triggered nanocavitation produces thermomechanical forces to locally regenerate SERS‐active nanogaps in protein‐rich biofluids while preserving optical performance.
Aditya Garg, Ze Zong, Meitong Nie, Stacie E. Deaver, Elizabeth M. Van Order, Elieser Mejia, Peter Vikesland, Erin S. Gloag, Wei Zhou   +8 more
wiley   +1 more source

Arthroscopic treatment of anterolateral impingement of the ankle

Acta Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated the mid-term results of patients who underwent arthroscopic surgery for chronic ankle pain due to anterolateral impingement.\nMethods: The study included twenty-eight patients (12 males, 16 females, mean age 32.5 years; range 14 ...
Mehmet Asik, Cengiz Sen, F. Erkal Bilen, Onder Kilicoglu, Mursel Debre, Omer F. Taser   +5 more
doaj  

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source