Results 71 to 80 of about 198,370 (383)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A Case of Immune Reconstitution Inflammatory Syndrome (IRIS) in Musculoskeletal Tuberculosis: A Rare Clinical Presentation in a 14-year-old Patient [PDF]

Journal of Clinical and Diagnostic Research
Tuberculosis associated- Immune Reconstitution Inflammatory Syndrome (TB-IRIS) is a paradoxical deterioration or resurgence of pre-existing tuberculous lesions, or the emergence of new lesions, in individuals who are effectively undergoing anti ...
Eswaran Mythilisri, B Vijay Anand, Ashlee Isaac, C Rishab   +3 more
doaj   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Abdominal dermocutaneous flap for reconstruction of a bleeding area in necrotizing fasciitis [PDF]

Revista Brasileira de Cirurgia Plástica, 2016
INTRODUCTION: The sequelae caused by Fournier's syndrome are extensive, systemic, debilitating, and deforming. They require both general and local treatments with antibiotics and subsequent debridement to delimit non-necrotic margins, which result from ...
Roger Nayef Fakhouri, Ricardo Baroudi
doaj   +1 more source

Evaluation of functional outcome and patient satisfaction after arthroscopic elbow arthrolysis [PDF]

, 2008
Arthroscopic arthrolysis is indicated for stiffness and pain caused by intrinsic stiffness and early arthritis of the elbow joint. Previous studies have demonstrated the benefits in relieving pain and improving motion, but none have reported the ...
Funk, L, Somanchi, BV
core  

A “Mesoporous Oxygen Chamber” Scaffold with Antibacterial and Early Immunomodulatory Effect for Promoting Bone Regeneration

Advanced Science, EarlyView.
In this study, an oxygen‐loaded and antimicrobial peptide (AP)‐functionalized scaffold (MBGAPO) is synthesized. With mesoporous structure of MBG applied as an “oxygen storage,” and AP‐provided antibacterial ability against E.coli and MRSA. MBGAPO exhibited osteogenic and multiplex‐immunomodulatory effects.
You Fu, Dan Lin, Zhicen Lu, Jian Wang, Jing Zhao, Zhiyuan Zhang, Bing Fang, Xiao Yang   +7 more
wiley   +1 more source

SPRK: A Low-Cost Stewart Platform For Motion Study In Surgical Robotics

, 2017
To simulate body organ motion due to breathing, heart beats, or peristaltic movements, we designed a low-cost, miniaturized SPRK (Stewart Platform Research Kit) to translate and rotate phantom tissue.
Goldberg, Ken, Goncalves, Aimee, Krishnan, Sanjay, Patel, Vatsal   +3 more
core   +1 more source

Outbreak of Aeromonas hydrophila wound infections association with mud football [PDF]

, 2004
On 16 February 2002, a total of 26 people presented to the emergency department of the local hospital in the rural town of Collie in southwest Western Australia with many infected scratches and pustules distributed over their bodies.
Amanda Whittle, Assanta MA, Bloch T, Brandi G, Burke V, Fulghum DD, Gary K. Dowse, Gold WL, Hassan Vally, Hazen TC, Houston CW, Kaper JB, Kelly KA, Scott Cameron, Semel JD, Tony Watson, Weber CA   +16 more
core   +1 more source

NIR‐II Responsive Multifunctional Scaffold Enabling “Kill‐Modulation‐Build” Synergistic Therapy for Infectious Bone Defects

Advanced Science, EarlyView.
A novel multifunctional scaffold with photothermal effects is developed for infected bone defect repair. It facilitates angiogenesis and osteogenesis while eliminating bacteria through hyperthermia. Additionally, the scaffold promotes macrophage polarization from M1 to M2 via ROS scavenging, enhancing anti‐inflammatory activity. This study demonstrates
Qifei Yang, Shu Lou, Yuan Zhang, Zhurun Fang, Changyue Xing, Wentao Wang, Minxuan Han, Zhendong Wang, Ben Zhong Tang, Ming Zhang   +9 more
wiley   +1 more source

Modified ulcer debridement in the treatment of the superficial fungal infection of the cornea [PDF]

International Journal of Ophthalmology, 2018
AIM: To evaluate the efficacy of modified corneal ulcer debridement in superficial fungal keratitis unresponsive to medications. METHODS: A total of 209 patients (209 eyes) with fungal keratitis, involving no more than 50% of the stromal depth and not ...
Jun-Yi Wang, Dian-Qiang Wang, Xiao-Lin Qi, Jun Cheng, Li-Xin Xie   +4 more
doaj   +1 more source