Results 121 to 130 of about 575,458 (256)
Advanced Healthcare Materials, EarlyView.Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran +15 more
wiley +1 more source
Ground-based optical position measurements of space debris in low earth orbits [PDF]
, 2013 The increasing amount of space debris requires the satellite operators to handle a growing number of collision risk assessments in order to eventually perform collision avoidance manoeuvrers.
Hampf, Daniel +4 more
core
Advanced Healthcare Materials, EarlyView.A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn +6 more
wiley +1 more source
Giving recovered materials new life
, 2021 For more than a century, Schnitzer Steel Industries, Inc. has been operating as a scrap-metal recycler, giving new life to old materials. Headquartered in Portland, they are one of three firms, along with Cherry City Metals and PNW Metal Recycling ...
core
Advanced Healthcare Materials, EarlyView.A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu +13 more
wiley +1 more source
Measuring Blood Plasma Glutamine Levels Using a Nanopore‐Based Sensor
Advanced Healthcare Materials, EarlyView.Glutamine (GLN) is a biomarker useful for predicting toxic ammonia accumulation. Here, we used a biosensor based on the Cytolysin A (ClyA) nanopore coupled with the GLN‐specific protein substrate‐binding domain 2 (SBD2) to demonstrate real‐time measurement of GLN in blood plasma, highlighting the potential for future point‐of‐care applications ...
Sofia B. Relvas +9 more
wiley +1 more source
Assessing the dynamic influences of slope angle and sediment composition on debris flow behaviour: An experimental approach [PDF]
, 2011 Debris flows are hazards that can inflict significant infrastructural damage and loss of life. Their rapid and unpredictable onset in isolated locations means that field studies are limited.
FAIRFIELD, GEORGINA
core
Advanced Healthcare Materials, EarlyView.CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli +8 more
wiley +1 more source
Laser based observation of space debris: Taking benefits from the fundamental wave [PDF]
, 2013 After the successful experimental demonstration of the prior published concept on laser-based monitoring of space debris in early 2012, we will present further technological and conceptual advancements of this position sensing scheme.
Hampf, Daniel +5 more
core
Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers
Advanced Healthcare Materials, EarlyView.Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li +9 more
wiley +1 more source