Results 161 to 170 of about 995,709 (250)

3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Advanced Robotics Research, EarlyView.
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix, Molly Carton, Olivia M. Young, Noah Barnes, Jordi T. Andreou, Sarah McHugh, Jack E. McCann, Claudia Davis, Victoria Reddig‐Leiman, Afsah Kamran, Dheeraj Gandhi, Miroslaw Janowski, Jeremy D. Brown, Mark Fuge, Axel Krieger, Clifford R. Weiss, Christopher R. Bailey, Ryan D. Sochol   +17 more
wiley   +1 more source

Lying Down Nystagmus in Lateral Canal Paroxysmal Positional Vertigo. [PDF]

Audiol Res
Gufoni M, Ducci N, Bernacca D, Califano L, Casani AP.   +4 more
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Efficacy of QMix with Canal Brush for Removal of Debris and Smear Layer in Root Canals Instrumented with ProTaper Next and WaveOne File.

J Pharm Bioallied Sci
Kumari RA, Madhudi VS, David AW, Ashwini KS, Jukanti A, Warad J.   +5 more
europepmc   +1 more source

An integrated multi-hazard assessment using machine learning in the complex terrains of Northern Pakistan. [PDF]

Sci Rep
Khan MI, Shafique M, Khattak GA, Yahya A, Badruddin IA.   +4 more
europepmc   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

ACSA2 is not astrocyte-specific: implications for cell sorting strategies in the rodent brain. [PDF]

Front Cell Neurosci
Daniele E, Khelifi G, Beretta D, Tsankov BK, Bang KWA, Beretta C, Philpott DJ, Hussein SM, Faiz M.   +8 more
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Long-Range Transport of Oil by Marine Plastic Debris: Evidence from an 8500 km Journey. [PDF]

Environ Sci Technol
James BD, Bezerra LEA, Buhler D, Cavalcante RM, Aguilera ML, Chen B, Gros J, Hanke UM, Lemkau KL, Nelson RK, Niles SF, de Oliveira AHB, Pitchford TD, Radović JR, Rodgers RP, Soares MO, Socolofsky SA, Summons RE, Swarthout RF, Teixeira CEP, Valentine DL, White HK, Yang M, Zanardi-Lamardo E, Zhang B, Reddy CM.   +25 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source