Results 211 to 220 of about 1,018,982 (351)

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

open access: yesAdvanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben   +8 more
wiley   +1 more source

Synthetic Hydrogels Incorporating Hydrolytic/Nonhydrolytic Macromer Ratios Exhibit Improved Tunability of In Vivo Degradation and Immune Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
A synthetic 4‐arm maleimide‐terminated poly(ethylene glycol) (PEG‐4MAL) hydrogel system that combines hydrolytic ester‐linked macromer (PEG‐4eMAL) with nondegradable amide‐linked macromer (PEG‐4aMAL) in various stoichiometric ratios to tune the degradability rate. The macromers are crosslinked with dithiothreitol via thiol‐maleimide click reaction. The
Michael D. Hunckler   +7 more
wiley   +1 more source

Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su   +5 more
wiley   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

open access: yesAdvanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng   +7 more
wiley   +1 more source

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