Results 41 to 50 of about 410,324 (293)

Towards Debris Information Analysis and Abstraction for Wi-Fi Radar Edge in Collapsed Structures

open access: yesIEEE Access, 2019
Structural collapses are widespread, owing to a surge in climatic changes, earthquakes, and terrorism. Therefore, there are some technological rescue methods in practice that involve sensors, radars, cameras, microphones, and robots.
Muhammad Faizan Khan   +2 more
doaj   +1 more source

Modelling the relative risk of plastic pollution to wildlife when data are scarce: an applied approach in the Mekong and Ganges river basins

open access: yesEnvironmental Research Letters, 2023
Plastic pollution of aquatic ecosystems is a growing environmental problem. Most plastic pollution originates from land-based sources and is transported via rivers, where plastic densities can exceed those at sea.
Qamar Schuyler   +3 more
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Origin and abundance of beach debris in the Balearic Islands

open access: yesScientia Marina, 2007
The abundance, nature and possible sources of litter on 32 beaches on the Balearic Islands (Mediterranean Sea) were investigated in 2005. Mean summer abundances in the Balearics reached approximately 36 items m-1, with a corresponding weight of 32±25 g m-
Lorena Martinez-Ribes   +3 more
doaj   +1 more source

Chemical-Physical Model of Gaseous Mercury Emissions from the Demolition Waste of an Abandoned Mercury Metallurgical Plant

open access: yesApplied Sciences, 2023
Soils from decommissioned Hg mine sites usually exhibit high levels of total mercury concentration. This work examines the behavior of mercury in the atmosphere on samples of contaminated debris of a demolished metallurgical plant present in La Soterraña
Rafael Rodríguez   +3 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

STar-DETR: A Lightweight Real-Time Detection Transformer for Space Targets in Optical Sensor Systems

open access: yesSensors
Optical sensor systems are essential for space target detection. However, previous studies have prioritized detection accuracy over model efficiency, limiting their deployment on resource-constrained sensors.
Yao Xiao   +5 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Histological evaluation of the root apices of failed endodontic cases

open access: yesSaudi Endodontic Journal, 2015
Aim: The aim of this histological study was to evaluate the different causes of the failures of the endodontic treatment. Materials and Methods: Adult patients who were referred for endodontic surgery and for whom root-end resection was considered ...
Camilla Nicole Pecora   +6 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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