Results 71 to 80 of about 1,047,819 (346)

A Spitzer IRS Study of Debris Disks Around Planet-Host Stars

, 2010
Since giant planets scatter planetesimals within a few tidal radii of their orbits, the locations of existing planetesimal belts indicate regions where giant planet formation failed in bygone protostellar disks.
Beichman, Beichman, Beichman, Bertone, Bessell, Bryden, Bryden, Bryden, Butler, C. A. Beichman, Carpenter, Chen, Chen, Cochran, Cutri, Dodson-Robinson, Fischer, Fischer, Geoffrey Bryden, Goldreich, Hauschildt, Hillenbrand, Høg, Ida, John M. Carpenter, Johnson, Johnson, Kurucz, Kóspál, Lawler, Moro-Martín, Peletier, Perryman, Quillen, Sarah E. Dodson-Robinson, Sato, Su, Tanner, Trilling, Valenti, Wright, Wright   +41 more
core   +1 more source

Marine debris ingestion by sea turtles (Testudines) on the Brazilian coast: an underestimated threat? [PDF]

, 2015
Assessment of marine debris ingestion by sea turtles is important, especially to ensure their survival. From January to December 2011, 23 specimens of five species of sea turtleswere found dead or dying after being rehabilitated ...
Barbosa, Bruno Corrêa, Carvalho, Robson Henrique, Lacerda, Pedro Dutra, Mendes, Sarah da Silva, Paschoalini, Mariana, Prezoto, Fábio, Sousa, Bernadete Maria de   +6 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Underestimated activity-based microplastic intake under scenario-specific exposures

Environmental Science and Ecotechnology
Despite increasing alarms over the health impacts of microplastics (MPs) due to their detection in human organs and feces, precise exposure evaluations remain scarce.
Kai Liu, Qingqing Li, Anthony L. Andrady, Xiaohui Wang, Yinan He, Daoji Li   +5 more
doaj   +1 more source

Impact of planet--planet scattering on the formation and survival of debris disks

, 2014
Planet--planet scattering is a major dynamical mechanism able to significantly alter the architecture of a planetary system. In addition to that, it may also affect the formation and retention of a debris disk by the system.
Marzari, F.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Propagation and deposition of stony debris flows at channel confluences [PDF]

, 2015
The fluid dynamics of stony debris flows generated in two small tributaries adjacent to each other and flowing into a main receiving channel was analyzed experimentally at a laboratory scale.
Foti, E., Lanzoni, Stefano, Stancanelli, LAURA MARIA   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Searching for signatures of planet formation in stars with circumstellar debris discs [PDF]

, 2015
(Abridged) Tentative correlations between the presence of dusty debris discs and low-mass planets have been presented. In parallel, detailed chemical abundance studies have reported different trends between samples of planet and non-planet hosts.
Eiroa, C., Maldonado, J., Montesinos, B., Mora, A., Villaver, E.   +4 more
core   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source