Results 71 to 80 of about 499,982 (305)

Preliminary design of debris removal missions by means of simplified models for low-thrust, many-revolution transfers [PDF]

, 2012
This paper presents a novel approach for the preliminary design of Low-Thrust (LT), many-revolution transfers. The main feature of the novel approach is a considerable reduction in the control parameters and a consequent gain in computational speed. Each
Vasile, Massimiliano, Zuiani, Federico, Federico Zuiani, Massimiliano Vasile   +3 more
core   +1 more source

Underestimated activity-based microplastic intake under scenario-specific exposures

Environmental Science and Ecotechnology
Despite increasing alarms over the health impacts of microplastics (MPs) due to their detection in human organs and feces, precise exposure evaluations remain scarce.
Kai Liu, Qingqing Li, Anthony L. Andrady, Xiaohui Wang, Yinan He, Daoji Li   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Development of a Debris Index [PDF]

, 2018
Environmental indices for space objects have been proposed to identify good candidates for active debris removal missions and to deal with the licensing process of space objects before their launch. A way to rank the environmental impact of spacecraft may be based on the assessment of how their fragmentations would affect operational satellites.
Letizia, Francesca, Colombo, Camilla, Lewis, Hugh G., Krag, Holger   +3 more
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Active debris removal mission from LEO with electric and hybrid propulsion [PDF]

, 2011
Debris proliferation in space environment is an impending problem for preserving future missions. Although prevention measures (IADC guidelines, NASA Handbook for Limiting Orbit Debris) with the intent to regulate and limit the space trac are adopted,
Sansica, A.
core  

Change in discharge state and effect of machining debris in electric discharge machining of permanent magnets with different initial magnetizing ratio

Nihon Kikai Gakkai ronbunshu, 2020
It is difficult to machine permanent magnets by traditional machining because of brittle-material and magnetic force, but EDM can machine permanent magnets easily.
Hideki TAKEZAWA, Shogo TOYAMA
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Meteorology and surface energy fluxes in the 2005–2007 ablation seasons at the Miage debris-covered glacier, Mont Blanc Massif, Italian Alps

, 2010
During the 2005–2007 June–September ablation seasons, meteorological conditions were recorded on the lower and upper parts of the debris‐covered ablation zone of Miage Glacier, Italy. In 2005, debris temperature and subdebris ice melt were also monitored
Mihalcea, Claudia, Diolaiuti, Guglielmina, G.A. Diolaiuti, Brock, Ben W., Kirkbride, Martin P., M. Kirkbride, C.E. Mihalcea, Cutler, Mark E. J.; id_orcid, C. Smiraglia, M. E. J. Cutler, Cutler, Mark, Brock, Benjamin, Kirkbride, Martin, Smiraglia, Claudio, B. W. Brock   +14 more
core   +1 more source