Results 71 to 80 of about 575,458 (256)

A Multi-Faceted Debris-Flood Hazard Assessment for Cougar Creek, Alberta, Canada

open access: yesHydrology, 2017
A destructive debris flood occurred between 19 and 21 June 2013 on Cougar Creek, located in Canmore, Alberta. Cougar Creek fan is likely the most densely developed alluvial fan in Canada.
Matthias Jakob   +4 more
doaj   +1 more source

Analytical model for the propagation of small debris objects clouds after fragmentations [PDF]

open access: yes, 2015
Current debris evolutionary models usually neglect fragments smaller than 10 cm because of the high computational effort they add to the simulation. However, small-debris objects can also be dangerous to operational satellites.
Colombo, Camilla   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Life cycle environmental assessment of marine debris and post-consumer waste plastics into asphalt pavements

open access: yesCleaner Environmental Systems
This study evaluates locally adapted recycling strategies for marine derelict fishing gear (DFG) and post-consumer waste (PCW) plastics in Hawaiʻi using a life cycle assessment (LCA) framework. Comparative cradle-to-gate LCAs were conducted to assess the
Mandy-Tanita Brinkmann   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Underestimated activity-based microplastic intake under scenario-specific exposures

open access: yesEnvironmental Science and Ecotechnology
Despite increasing alarms over the health impacts of microplastics (MPs) due to their detection in human organs and feces, precise exposure evaluations remain scarce.
Kai Liu   +5 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Debris cleanup crews help unearth time capsule

open access: yes, 2021
The Vida McKenzie Community Center, located along the McKenzie River near Vida in Lane County, has long served as a local spot for family gatherings and other celebrations.

core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Powering homes in Jackson County with locally-sourced biofuel

open access: yes, 2021
Biomass One, L.P. has been independently producing power by processing woody debris on site since 1990. Based in Jackson County, the facility is contracted with the Debris Management Task Force to receive woody debris from the Almeda Drive Fire area ...

core  

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