Results 181 to 190 of about 1,553,048 (247)

Accelerating glacier recession contrasts rock glacier stability in a temperate mountain range. [PDF]

open access: yesSci Adv
Khatiwada A   +11 more
europepmc   +1 more source

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao   +15 more
wiley   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

open access: yesAdvanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu   +7 more
wiley   +1 more source

Society for Maternal-Fetal Medicine Special Statement: Reducing the risk of transmitting infection during ultrasound examination-Updated 2026. [PDF]

open access: yesPregnancy (Hoboken)
Society for Maternal‐Fetal Medicine (SMFM)   +3 more
europepmc   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

open access: yesAdvanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong   +15 more
wiley   +1 more source

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

open access: yesAdvanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan   +13 more
wiley   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

open access: yesAdvanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen   +4 more
wiley   +1 more source

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