Results 111 to 120 of about 506,489 (355)

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

open access: yesAdvanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao   +11 more
wiley   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

A new statistical method to assess potential debris flow erosion [PDF]

open access: diamond, 2023
G. Bertoldi   +3 more
openalex   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Spatio-temporal variability in debris-flow activity: a tree-ring study at Geisstriftbach (Swiss Alps) extending back to AD 1736 [PDF]

open access: yes, 2018
Past debris-flow activity on the forested cone of the Geisstriftbach torrent (St. Niklaus, Valais, Swiss Alps) was assessed from growth disturbances in old conifer trees, providing a much improved record of past events.
Bollschweiler, Michelle   +3 more
core  

A Biologically‐Architected Wear and Damage‐Resistant Nanoparticle Coating From the Radular Teeth of Cryptochiton stelleri

open access: yesAdvanced Functional Materials, EarlyView.
The ultrahard teeth of mollusks that feed on rocky substrates contain a wear‐resistant coating on their surfaces consisting of densely packed mesocrystalline magnetic nanoparticles within an organic matrix. These coatings display significant hardness and toughness through their highly controlled mesocrystalline architectures.
Taifeng Wang   +7 more
wiley   +1 more source

Rainfall characteristics for periglacial debris flows in the Swiss Alps: past incidences-potential future evolutions [PDF]

open access: yes, 2018
Based on observational meteorological data since A.D. 1864 and tree-ring records of debris-flow activity, this paper assesses changes in rainfall characteristics and their impact on the triggering of geomorphic events in a high-elevation watershed of the
Beniston, Martin   +2 more
core  

Living Liquid Metal Composites Embedded with Electrogenic Endospores for Next‐Generation Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
A new class of living liquid metal composites is introduced, embedding Bacillus subtilis endospores into eutectic gallium–indium (EGaIn). The spores enhance droplet coalescence, strengthen interfacial conductivity, and provide on‐demand electrogenic functionality after germination. The composites exhibit high conductivity, self‐healing, patternability,
Maryam Rezaie, Yang Gao, Seokheun Choi
wiley   +1 more source

Extreme climate and human activities contribute to low-frequency, large-scale catastrophic debris flow: a case study in the Heishui Gully

open access: yesGeomatics, Natural Hazards & Risk
Rainfall is an excitation factor for rainfall-type debris flows, and high-frequency rainfall commonly does not directly trigger large-scale catastrophic debris flows.
Wentao Zhou   +6 more
doaj   +1 more source

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