Results 251 to 260 of about 513,388 (355)

Passive Water Intake Screen to Reduce Entrainment of Debris and Aquatic Organisms Under Various Hydraulic Flow Conditions [PDF]

Agata Pawłowska-Salach, Michał Zielina, Karol Kaczmarski   +2 more
openalex   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Numerical model of debris flow susceptibility using slope stability failure machine learning prediction with metaheuristic techniques trained with different algorithms. [PDF]

Sci Rep
Onyelowe KC, Moghal AAB, Ahmad F, Rehman AU, Hanandeh S.   +4 more
europepmc   +1 more source

Characteristics of landslide-debris flow accumulation in mountainous areas. [PDF]

Heliyon, 2019
Qing-Zhao Z, Qing P, Ying C, Ze-Jun L, Zhen-Ming S, Yuan-Yuan Z.   +5 more
europepmc   +1 more source

Mechanism of enhanced mobility of glacial debris flows induced by ice and rock avalanches in southeast Tibet, China: Insights from impact loading tests [PDF]

Yao Jiang, Xingsheng Lu, Jiao Wang, Guotao Zhang, Gonghui Wang, Tao Wang, Zhi Zhang, Tongjie Ren, Haotian Lu   +8 more
openalex   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Field physical model tests on the mechanism of river blocking by debris flow in the middle reaches of the Dadu River, Southwest China. [PDF]

PLoS One
Song Z, Zhan Y, Chen Y, Fan G.
europepmc   +1 more source

Dynamic effects induced by the impact of debris flows on protection barriers

, 2018
Marchelli, Maddalena
openalex   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source