Results 161 to 170 of about 8,738 (313)

Art and Urban Decadence [PDF]

open access: yes, 2020
Garcia, Beatriz
core  

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Controlled Engineering of 2D Alkali‐Iron‐Chloride Compounds and Lateral Quantum Heterostructures Within Confined Graphene Nanoreactors

open access: yesAdvanced Functional Materials, EarlyView.
This work presents a programmable atomic engineering strategy for 2D materials using Å‐scale nanoreactors formed by bilayer graphene (BLG) intercalation. A new class of alkali‐iron‐chloride compounds, along with lateral heterostructures composed of monolayer alkali halides and iron chlorides, is revealed.
Haiming Sun   +6 more
wiley   +1 more source

Mesoscale Domain Evolution Mechanism during Alternating Current (AC) Poling of Relaxor Ferroelectrics

open access: yesAdvanced Functional Materials, EarlyView.
Ferroelectric domain variants that are energetically equivalent are expected to remain preserved during polarization reversal. However, phase‐field simulations reveal that inclined domain walls in relaxor ferroelectrics can undergo irreversible elimination during alternating current poling through a proximity effect driven by long‐range elastic ...
Yuan‐Jie Sun   +2 more
wiley   +1 more source

All‐Solution‐Processed HgTe Quantum Dot Photodetectors for Extended Short‐Wavelength Infrared Range Enhanced by Plasmonic ITO Nanocrystals

open access: yesAdvanced Functional Materials, EarlyView.
All‐solution‐processed, low‐cost extended short‐wavelength infrared photodetectors are realized by coupling colloidal HgTe quantum dots to plasmonic In2O3:Sn,F nanocrystals. Localized surface plasmon resonances boost and spectrally tailor light absorption between 1500 and 3000 nm, enabling responsivities above 40 A W−1.
Kseniia A. Sergeeva   +9 more
wiley   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

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