Results 141 to 150 of about 213 (192)

Tips for Successful Arthroscopic Single‐Bundle Posterior Cruciate Ligament Reconstruction

open access: yesArthroscopy Techniques, EarlyView.
Abstract Injuries to the posterior cruciate ligament (PCL) are relatively common knee injuries often seen in the setting of multiligamentous knee injuries. Operative treatment for PCL injuries has been described using both single and double bundles with both open and arthroscopic techniques.
Neil Patel   +5 more
wiley   +1 more source

Distal Biceps Tendon Anatomical All‐Suture Anchor Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract This technical note describes a single‐incision, onlay, double all‐suture anchor technique for distal biceps tendon repair. The method enables anatomic reattachment of the tendon onto the ulnar aspect of the radial tuberosity, optimizing footprint restoration and tendon‐bone contact area compared with conventional single‐incision techniques ...
Afsana Hasan   +6 more
wiley   +1 more source

A Technique for Patellar Tendon Repair Using a Suture‐Free Nonwoven Polyethylene Terephthalate Implant

open access: yesArthroscopy Techniques, EarlyView.
Abstract Surgical repair remains the standard of care for complete patellar tendon ruptures. However, healing is often challenging due to the tendon's poor biological environment and high tensile stress at the repair site. Bioinductive implants have been introduced to enhance tendon healing; however, they often lack early structural reinforcement. This
McKenzie A. Mayer   +4 more
wiley   +1 more source

Lateral Meniscus Oblique Radial Tear All‐Inside Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract Lateral meniscus oblique radial tears, particularly high‐grade types 3 and 4, are common in acute anterior cruciate ligament injuries and contribute to significant knee instability and meniscal extrusion if left unrepaired. Surgical repair is necessary to restore normal knee kinematics and meniscal function.
Patrick M. Ryan   +4 more
wiley   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar   +6 more
wiley   +1 more source

A Practical Gut‐On‐Chip Workflow for Imaging‐Based Assessment of Epithelial Barrier Dynamics During E. coli Co‐Culture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The intestinal epithelium and its resident microbiota form a dynamic interface that is central to gut homeostasis, but this interface is difficult to model with conventional tools. Static Transwell cultures lack physiological fluid shear, whereas animal models are costly and poorly suited to quantitative, high‐content imaging.
Shih‐Wei Chiang   +2 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

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