AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model
Kanamycin plus furosemide (KM + FU) treatment (acute ototoxic model) causes AMPKα activation and rapidly induces cochlear outer hair cell (OHC) loss. Silencing AMPKα1 via posterior semicircular canal injection 48 h before KM + FU treatment reduces this damage, preserving OHCs and hearing.
Shengyu Zou +6 more
wiley +1 more source
Use of ultrasonic aspirator for decalcifying the mitral annulus during mitral valve replacement. [PDF]
Anzai IA, Geirsson A.
europepmc +1 more source
Abstract Cold weather conditions impose substantial constraints upon the performance and long‐term resilience of concrete materials. Alkali‐activated slag (AAS) presents itself as a promising substitute, exhibiting sustained hydraulic activity even when exposed to ambient conditions characterized by low temperatures.
Zeynep Bahçeci +3 more
wiley +1 more source
Extensive posterior bar decalcification with novel calcific emulsification to enable endoscopic minimally invasive mitral valve repair. [PDF]
Rheault-Henry M, Chu MWA.
europepmc +1 more source
Abstract Ground granulated blast‐furnace slag (GGBS) is a widely used clinker substitute in concrete, recognized for its potential to significantly reduce environmental impacts. However, its application in prestressed concrete remains limited in several countries, mainly due to concerns regarding early‐age mechanical performance and long‐term ...
D. Rolando Baldiviezo +6 more
wiley +1 more source
Editorial: Temporal bone histopathology: updates for neurotology. [PDF]
Gelaye BK, Moghimi M, Redleaf M.
europepmc +1 more source
Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An +7 more
wiley +1 more source
Sustainable enhancement of chemical durability and microstructural stability in cement mortar incorporating sodium silicate-silica fume treated recycled fine aggregate. [PDF]
Shaju AC +5 more
europepmc +1 more source
An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda +6 more
wiley +1 more source
Long-Term Strength Development and Microstructural Characteristics of High-Content Cemented Soil Under Seawater Exposure. [PDF]
Pan H, Wang W, Zhou J, Cheng X, Hu G.
europepmc +1 more source

