Results 31 to 40 of about 22,305 (265)

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Effect of decalcification on immunohistochemical staining of trichorhinophalangeal syndrome type 1

open access: yesPrecision Medical Sciences
To evaluate the effect of different decalcification solutions on the immunohistochemical staining of trichorhinophalangeal syndrome type 1 (TRPS1), and to provide a reliable basis for the accurate diagnosis of bone metastasis of breast cancer. Due to the
Chen Miao, Gang Chen, Wenli Han, Ran Hu
doaj   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Decalcification

open access: yes, 2014
Author: University of Nottingham Medical School Division of Histopathology ### Method: Many surgical specimens contain calcified areas which need to be decalcified before processing and sectioning. This is achieved as follows. 1. When the specimen is sufficiently fixed the selected tissue is placed into a labelled pot of 8% formic acid and left on ...
openaire   +2 more sources

A novel method of decalcification of bone by heat-accelerated method with tissue floatation bath using nitric acid and formic Acid: A comparative study

open access: yesJournal of International Clinical Dental Research Organization, 2022
Context: Decalcification of bone is a challenging aspect since penetration of decalcifying agents through dense alveolar bone is a slow process. Striking the right balance between speed and quality of staining is essential for accurate and timely ...
Amruta Hiraman Galphade   +3 more
doaj   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

open access: yesAdvanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin   +9 more
wiley   +1 more source

Comparative study of modified EDTA decalcification and acid decalcification in immunohistochemistry of breast cancer with bone metastasis

open access: yesZhongguo aizheng zazhi, 2019
Background and purpose: The incidence of bone metastasis in advanced breast cancer (BC) is more than 70%, and decalcification of bone tissue is a technical difficulty.
SUN Jing   +6 more
doaj  

Qualitative Histological Evaluation of Hard and Soft Tissue Components of Human Permanent Teeth Using Various Decalcifying Agents - A Comparative Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Introduction: Decalcification is the commonly employed technique in histopathology laboratories as a part of calcified tissue preparation for the microscopic examination.
Sonia Gupta   +3 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Decalcify cardiac CT: unveiling clearer images with deep convolutional neural networks

open access: yesFrontiers in Medicine
Decalcification is crucial in enhancing the diagnostic accuracy and interpretability of cardiac CT images, particularly in cardiovascular imaging. Calcification in the coronary arteries and cardiac structures can significantly impact the quality of the ...
Gopinath Nagarajan   +9 more
doaj   +1 more source

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