Results 41 to 50 of about 19,514,073 (287)

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Modeling of natural circulation for the inherent safety analysis of sodium cooled fast reactors

Nuclear Energy and Technology, 2016
The paper discusses a set of developed integrated one-dimensional models of thermal-hydraulic processes that contribute to the removal of decay heat in a BN-type reactor.
A.S. Bochkarev, P.N. Alekseev, A.S. Korsun, V.S. Kharitonov   +3 more
doaj   +1 more source

Utilization of temperature kinetics as a method to predict treatment intensity and corresponding treated wood quality : durability and mechanical properties of thermally modified wood [PDF]

, 2014
Wood heat treatment is an attractive alternative to improve decay resistance of wood species with low natural durability. However, this improvement of durability is realized at the expense of the mechanical resistance.
GERARDIN, Phillipe, Hannouz,S, Gérardin,P, Gérardin, P., Dumarçay,S, Pétrissans, M., Collet,R, Pétrissans,M, Dumarçay, S., Pétrissans, A., Pétrissans,A, Elaieb, Mohamed Tahar, HANNOUZ, Simon, Candelier,K, PETRISSANS, Mathieu, Collet, R., Hannouz, S., Elaieb,M, Candelier, K., ELAIEB, Mohamed, CANDELIER, Kévin, PETRISSANS, Anelie, DUMARÇAY, Stéphane, Gérardin, Philippe, Elaieb, M., COLLET, Robert   +25 more
core   +1 more source

Microstructure Reconstruction in Battery Electrodes Using Machine Learning Based on Low‐Voltage Focused Ion Beam–Scanning Electron Microscopy Tomography Images

Advanced Engineering Materials, EarlyView.
Low‐voltage FIB‐SEM tomography combined with a image preprocessing pipeline improves phase contrast and enables reliable machine‐learning segmentation of conductive networks in lithium‐ion battery electrodes. Structural descriptors are extracted from segmented images, done semimanually and automated, and compared.
Lisa Beran, Vincent Nebel, Dominik Perius, Kshitij Kumar, Yannis Heim, Laura Bies, Tobias Kraus   +6 more
wiley   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

Advanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle, Cesar Alvarez‐Llamas, Vincent Motto‐Ros, Christophe Dujardin, Jérémie Margueritat, David Rodney   +5 more
wiley   +1 more source

Safety analysis of increase in heat removal from reactor coolant system with inadvertent operation of passive residual heat removal at no-load conditions

Nuclear Engineering and Technology, 2015
The advanced passive pressurized water reactor (PWR) is being constructed in China and the passive residual heat removal (PRHR) system was designed to remove the decay heat. During accident scenarios with increase of heat removal from the primary coolant
Ge Shao, Xuewu Cao
doaj   +1 more source

OntOMat: Toward Ontology‐Based Product and Process Design Engineering and Optimization Solutions Fueling Circular Value Chains

Advanced Engineering Materials, EarlyView.
The OntOMat ontology establishes a structured framework for polymer matrix fiber reinforced composite materials, integrating manufacturing processes, characterization methods, and multiscale design through the VDI/VDE 3682 formalized process description standard.
Nicolas Christ, Jörg Hohe, Martin Kördel, Michael Giese, Niklas Toffert, Christian Seidel, Olaf Rehme, Patrik Schneider, Oliver Focke, Elie Abi Aoun, Claas Falldorf, Beñat Gutierrez, Alexandra Kühn, Sven Torstrick-von der Lieth, Christoph Herden, Erik Johannsen, Jan‐Uwe R. Schmidt, Felix Winkelmann, Andreas Schott, Daniel Schott   +19 more
wiley   +1 more source

Natural circulation decay heat removal from an SP-100, 550 kWe power system for a lunar outpost [PDF]

, 1992
This research investigated the decay heat removal from the SP-100 reactor core of a 550-kWe power system for a lunar outpost by natural circulation of lithium coolant.
El-Genk, Mohamed S., Xue, Huimin
core  

Thermal-hydraulic analysis of an innovative decay heat removal system for lead-cooled fast reactors [PDF]

, 2016
Improvement of safety requirements in GEN IV reactors needs more reliable safety systems, among which the decay heat removal system (DHR) is one of the most important.
GIANNETTI, FABIO, VITALE DI MAIO, DAMIANO, NAVIGLIO, Antonio, CARUSO, Gianfranco   +3 more
core   +1 more source

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source