Results 41 to 50 of about 183,014 (291)

ASSESSMENT OF CONDENSATION HEAT TRANSFER MODEL TO EVALUATE PERFORMANCE OF THE PASSIVE AUXILIARY FEEDWATER SYSTEM

Nuclear Engineering and Technology, 2013
As passive safety features for nuclear power plants receive increasing attention, various studies have been conducted to develop safety systems for 3rd-generation (GEN-III) nuclear power plants that are driven by passive systems.
YUN-JE CHO, SEOK KIM, BYOUNG-UHN BAE, YUSUN PARK, KYOUNG-HO KANG, BYONG-JO YUN   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Spatially Resolved Monitoring of Drying of Hierarchical Porous Organic Networks [PDF]

, 2016
Evaporation kinetics of water confined in hierarchal polymeric porous media is studied by low field nuclear magnetic resonance (NMR). Systems synthesized with various degrees of cross-linker density render networks with similar pore sizes but different ...
Acosta, Rodolfo Hector, Gomez, Cesar Gerardo, Mattea, Carlos, Monti, Gustavo Alberto, Silletta, Emilia Victoria, Stapf, Siegfried, Strumia, Miriam Cristina, Velasco, Manuel Isaac   +7 more
core   +1 more source

Natural circulation characteristics of main loop after shutdown of liquid-fuel molten salt reactor

He jishu
BackgroundThe molten salt reactor (MSR) is one of the six advanced reactors identified by the Generation IV International Forum. The MSR exhibits unique characteristics, such as intrinsic safety, sustainable development, nuclear nonproliferation, natural
XUE Shuaiyu, ZHOU Chong, ZOU Yang, XU Hongjie   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Thermal compression of atomic hydrogen on helium surface [PDF]

, 2006
We describe experiments with spin-polarized atomic hydrogen gas adsorbed on liquid $^{4}$He surface. The surface gas density is increased locally by thermal compression up to $5.5\times10^{12}$ cm$^{-2}$ at 110 mK.
A. Matsubara, A.I. Safonov, A.I. Safonov, A.I. Safonov, B.V. Svistunov, B.W. Statt, B.W. Statt, C.P. Poole, D.S. Petrov, D.S. Zimmerman, E.S. Meyer, H.P. Godfried, I. Shinkoda, I.A. Yu, J. Ahokas, J. Järvinen, J. Järvinen, J.J. Berkhout, M.W. Reynolds, N. Prokofev, O.V. Lounasmaa, S. Vasiliev, S. Vasilyev, S.A. Vasiliev, S.A. Vasiliev, S.A. Vasiliev, S.A. Vasiliev, U. Al Khawaja, V.L. Berezinskii, Y.P. Zhang, Yu. Kagan, Z. Hadzibabic   +31 more
core   +1 more source

Modeling of natural circulation for the inherent safety analysis of sodium cooled fast reactors

Nuclear Energy and Technology, 2016
The paper discusses a set of developed integrated one-dimensional models of thermal-hydraulic processes that contribute to the removal of decay heat in a BN-type reactor.
A.S. Bochkarev, P.N. Alekseev, A.S. Korsun, V.S. Kharitonov   +3 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source