Results 171 to 180 of about 9,708,981 (308)

Theoretical georeferenced potential for biomethane production in Brazil from organic waste, including logistics and cost aspects

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract One of the challenges for biomethane production in Brazil, as well as its use, is related to transportation logistics, owing to the lack of detailed studies of the entire supply chain at a national level, which includes all the stages from waste collection to transportation for its final use.
Andreza Nascimento Vaz, Electo Eduardo Silva Lora, Ana Paula Mattos, Leonardo Peña Pupo, Matheus Siqueira Barros, Olasunkanmi Opeoluwa Adeoye   +5 more
wiley   +1 more source

Reframing decentralized diagnostics with a programmable multi-dimensional microfluidic system. [PDF]

Nat Commun
Xu T, Zhang Y, Tang X, Wei H, Kang L, Zhou Q, Li S, Zhao X, Li J, Zhang Z, Wan C, Zhang Y, Chen D, Tian Y, Liu BF, Chen P.   +15 more
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Decentralized Clinical Trials in Oncology-A Radiological Perspective. [PDF]

Korean J Radiol
Yi W, Lee HJ, Kim N, Na S, Kim M, Shim H, Yoo H, Kim KW.   +7 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

VISIONARA - developing a concept for decentralized competency-based learning in primary health care and its proposed evaluation. [PDF]

GMS J Med Educ
Lübbert J, Schüle D, Wachter C, Kurczyk S, Altiner A, Loukanova S, Leutgeb R.   +6 more
europepmc   +1 more source

‘Self’ and ‘othering’ as a byproduct of large‐scale assessment: An investigation into the Gaokao retake policy

British Educational Research Journal, EarlyView.
Abstract While Gaokao, the National College Entrance Examination (NCEE), has been extensively discussed outside the Chinese academic circle, the retake policy of the test has not received much attention. Moreover, Gaokao research in China has predominantly examined the effectiveness of the retake decision in relation to students' demographic ...
Yifeng Cheng, M. Obaidul Hamid
wiley   +1 more source

Patient-operated imaging for clinical assessment: regulatory and reimbursement challenges in European health systems. [PDF]

Front Digit Health
Fenton C, Tibi C, Glazer J, Prisant N.
europepmc   +1 more source