Results 191 to 200 of about 9,065,158 (302)

Rethinking Phase I units in the era of immuno-oncology: a three-layer framework. [PDF]

J Immunother Cancer
Sun L, Xu R, Wang S, Li N.
europepmc   +1 more source

Inventory Replenishment and Transshipment for Distributed Autologous Cell Therapy Manufacturing Networks

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Autologous cell therapy (AuCT) manufacturing networks must balance two competing objectives: reducing cost and improving patient access to time‐sensitive therapy. This study compares three AuCT manufacturing network designs: a centralized network with a single manufacturing facility, a coordinated point‐of‐care (POC) network in which POCs can ...
Zhaowei Li, Chelsea C. White III, Kan Wang, Ben Wang   +3 more
wiley   +1 more source

MediHive: A Decentralized Agent Collective for Medical Reasoning. [PDF]

J Healthc Inform Res
Wang X, Yang CC.
europepmc   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

From spillover to systems: evidence gaps in One Health preparedness for emerging infectious diseases in Latin America and the Caribbean. [PDF]

Front Med (Lausanne)
Ortiz-Prado E, Cadena MP, Vasconez-Gonzalez J, Izquierdo-Condoy JS.   +3 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

From production to bedside: A tiered QC framework for regulatory alignment and analytical comparability in decentralized CGT. [PDF]

Regen Ther
Nahum S, Doshi D, Kosnik C, Jeffries E, Nishida K, Caplan V, Leyen HV.   +6 more
europepmc   +1 more source

Toward the harmonization of bioequivalence guidelines in Europe: Commentary on the state of the art and future priorities under ICH M13A for immediate‐release oral forms

British Journal of Clinical Pharmacology, EarlyView.
Domenico Nocera, Giusi Forastiero, Andrea Logreco, Alessia Proietti, Antonio Galluccio, Carlotta Lunghi, Elisabetta Poluzzi, Fabrizio De Ponti   +7 more
wiley   +1 more source

Kin discrimination in plants: overview and implications for population and community ecology

Biological Reviews, EarlyView.
ABSTRACT Following the discovery of identity discrimination, particularly self and kin discrimination amongst plant competitors, research on interplant interactions has advanced significantly within plant physiology and evolutionary ecology. This review synthesizes current knowledge on how both self and kin discrimination influence plant growth ...
Akira Yamawo
wiley   +1 more source

Security enhancement using scalable Blockchain-based Multi-Factor Authentication (BMFA). [PDF]

PLoS One
Rahman F, Fatima A, Hassan M, Al-Zyoud M, Alfaidi A, Maktoof MAJ, Ghazal TM.   +6 more
europepmc   +1 more source