Results 91 to 100 of about 47,932 (337)

Formalizing Constructive Quantifier Elimination in Agda

open access: yes, 2018
In this paper a constructive formalization of quantifier elimination is presented, based on a classical formalization by Tobias Nipkow. The formalization is implemented and verified in the programming language/proof assistant Agda.
Pope, Jeremy
core   +1 more source

On deciding how to decide: Designing participatory budget processes

open access: yesEuropean Journal of Operational Research, 2013
Abstract Participatory budgets are becoming increasingly popular in many municipalities all around the world. The underlying idea is to allow citizens to participate in the allocation of a municipal budget. Many advantages have been suggested for such experiences, including legitimization and more informed and transparent decisions.
Cesar Alfaro   +3 more
openaire   +2 more sources

Trustworthy AI: Deciding What to Decide

open access: yes, 2023
When engaging in strategic decision-making, we are frequently confronted with overwhelming information and data. The situation can be further complicated when certain pieces of evidence contradict each other or become paradoxical. The primary challenge is how to determine which information can be trusted when we adopt Artificial Intelligence (AI ...
Wu, Caesar   +4 more
openaire   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

New values of the Julia Robinson number

open access: yesCubo
We extend results of Vidaux and Videla concerning the set of Julia Robinson numbers.
Carlos Muñoz Sandoval
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

The First-Order Theory of Sets with Cardinality Constraints is Decidable

open access: yes, 2004
We show that the decidability of the first-order theory of the language that combines Boolean algebras of sets of uninterpreted elements with Presburger arithmetic operations. We thereby disprove a recent conjecture that this theory is undecidable.
Kuncak, Viktor, Rinard, Martin
core   +3 more sources

Gradual Certified Programming in Coq

open access: yes, 2015
Expressive static typing disciplines are a powerful way to achieve high-quality software. However, the adoption cost of such techniques should not be under-estimated.
Disney T.   +7 more
core   +3 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Does Science Progress Towards Ever Higher Solvability Through Feedbacks Between Insights and Routines?

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxii2.09 The affirmative answer to the title question is justified in two ways: logical and empirical. (1) The logical justification is due to Gödel’s discovery (1931) that in any axiomatic formalized theory, having ...
Witold Marciszewski
doaj  

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