Results 71 to 80 of about 475,794 (375)

Deciding not to decide: Deferral in constitutional design

open access: yesInternational Journal of Constitutional Law, 2011
In designing constitutions, constitutional drafters often face constraints that cause them to leave things “undecided”—or to defer decision-making on certain constitutional issues to the future. They do this both through adopting vague constitutional language, and through specific language that explicitly delegates issues to future legislators (i.e ...
Dixon, Rosalind, Ginsburg, Tom
openaire   +2 more sources

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Boundedness in languages of infinite words [PDF]

open access: yesLogical Methods in Computer Science, 2017
We define a new class of languages of $\omega$-words, strictly extending $\omega$-regular languages. One way to present this new class is by a type of regular expressions.
Mikołaj Bojańczyk, Thomas Colcombet
doaj   +1 more source

Pausing to decide [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
Sudden environmental changes and physiological stresses such as osmotic shock, nutrient availability, and heat shock demand that cells have the abilities to modulate their behavior to adapt and survive. Eukaryotic cells face the additional challenges of coordinating these changes between different cellular compartments, and this coordination ...
Peter Walter, Maho Niwa
openaire   +3 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Deciding some displayable modal logics [PDF]

open access: yesarXiv, 2023
In this paper we use display calculus to show the decidability for normal modal logic K and some of its extensions.
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

A Decidable Extension of Data Automata [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2011
Data automata on data words is a decidable model proposed by Bojańczyk et al. in 2006. Class automata, introduced recently by Bojańczyk and Lasota, is an extension of data automata which unifies different automata models on data words.
Zhilin Wu
doaj   +1 more source

Undecidability and Complexity for Super-Turing Models of Computation

open access: yesProceedings, 2022
It seems that intelligent complex systems will require formalisms having richer behavior than Turing machines. Very little is known about the relations (e.g., the expressiveness and/or effectiveness) between new super-Turing models of computation.
Eugene Eberbach
doaj   +1 more source

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