Results 81 to 90 of about 494,097 (364)

On Decidability of Hyperbolicity

open access: yesCombinatorica, 2022
We prove that a wide range of coloring problems in graphs on surfaces can be resolved by inspecting a finite number of configurations.
Dvořák, Zdeněk, Postle, Luke
openaire   +2 more sources

Topological Semantics and Decidability [PDF]

open access: yes, 2007
It is well-known that the basic modal logic of all topological spaces is $S4$. However, the structure of basic modal and hybrid logics of classes of spaces satisfying various separation axioms was until present unclear. We prove that modal logics of $T_0$
Sustretov, Dmitry
core   +6 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Boundedness in languages of infinite words [PDF]

open access: yesLogical Methods in Computer Science, 2017
We define a new class of languages of $\omega$-words, strictly extending $\omega$-regular languages. One way to present this new class is by a type of regular expressions.
Mikołaj Bojańczyk, Thomas Colcombet
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

A Syntactic Proof of the Decidability of First-Order Monadic Logic

open access: yesBulletin of the Section of Logic
Decidability of monadic first-order classical logic was established by Löwenheim in 1915. The proof made use of a semantic argument and a purely syntactic proof has never been provided.
Eugenio Orlandelli, Matteo Tesi
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

A Decidable Extension of Data Automata [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2011
Data automata on data words is a decidable model proposed by Bojańczyk et al. in 2006. Class automata, introduced recently by Bojańczyk and Lasota, is an extension of data automata which unifies different automata models on data words.
Zhilin Wu
doaj   +1 more source

Quadratic Word Equations with Length Constraints, Counter Systems, and Presburger Arithmetic with Divisibility

open access: yes, 2018
Word equations are a crucial element in the theoretical foundation of constraint solving over strings, which have received a lot of attention in recent years. A word equation relates two words over string variables and constants.
A Kiezun   +21 more
core   +1 more source

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