Results 81 to 90 of about 3,649,113 (248)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
La cuestión de la moral en Ser y tiempo de Martin Heidegger
Arbor: Ciencia, Pensamiento y Cultura, 2015 Se puede ver en Ser y tiempo el intento de establecer una moral de la autenticidad, pues la vida humana se considera como constante proyectarse hacia adelante, estableciendo metas e intentando cumplirlas a partir de la decisión y de la responsabilidad ...
Vicente Lozano Díaz
doaj +1 more source
Economic regimes identification using machine learning technics [PDF]
, 2018 43 páginas.Trabajo de Máster en Economía, Finanzas y Computación. Director: Dr. José Manuel Bravo Caro. Economic conditions over long time periods can be distinguished by regimes.
Caki, Mamed
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Decisión making and decisión support systems for balancing Socio-Economic and Natural Capital Development. [PDF]
The paper discusses briefly a hierarchical spatio-temporal framework to study globalization, economics and ecology for better understanding and conceptualization of the balance between biodiversity and Natural Capital (NC) on one side, and the Socio ...
Vadineanu, Angheluta
core +1 more source
Philosophical Dialogue and Military Decision Making [PDF]
, 2015 : The military establishment plays an important role in society, not only because it is pivotal in securing the state from external and internal threats but also because the conduct of soldiers affect the fortunes of the state both fiscally and morally ...
Ikpe, Ibanga
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Actualidades Investigativas en Educación, 2008 El trabajo tiene como propósito dar a conocer los resultados de la utilización del estudio de casos, la simulación y la elaboración de mapas conceptuales como técnicas didácticas en los procesos de enseñanza y de aprendizaje de la negociación y la ...
Evelyn Hernández Ortíz
doaj +1 more source
Familias refugiadas iraquíes en Jordania: la búsqueda activa de soluciones [PDF]
, 2016 Para los refugiados iraquíes en Jordania la decisión de partir hacia Europa se ve muy influida por su experiencia mientras esperan en esta ...
Twigt, Mirjam A.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source