Results 81 to 90 of about 308,696 (151)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Discrecionalidad, ciencia y sistema del derecho penal
Pensamiento Jurídico, 2017 Los teóricos del derecho penal casi de manera unánime sostienen que el derecho penal es una ciencia, dicha afirmación es fundamental para los términos en que se desarrolla su construcción, dado que la cientificidad permite a este conocimiento una ...
André Scheller D´Angelo
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Tecnología y Ciencia, 2018 El presente trabajo se propone analizar la aplicación de una herramienta de software basada en lógica difusa, para la identificación de la localización sustentable de cuatro parques industriales ubicados en la provincia de Córdoba.
Pablo Modini
doaj
La aversión al riesgo en la toma de decisiones médicas: una revisión
Lecturas de Economía, 2011 El artículo presenta una revisión de literatura sobre la aversión al riesgo en la toma de decisiones médicas. Se cubrieron las bases de datos Econlit, Jstor, Science Direct y Springer Link desde 1985.
Liliana Chicaíza +2 more
doaj
Trajectory-Based Behavioral Analytics for Blockchain Systems
AlgorithmsBlockchain systems generate massive volumes of transactional data, yet most existing analytical approaches rely on query-based retrieval mechanisms that treat transactions as isolated records.
Francisco Javier Moreno Arboleda +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Estudios Eclesiásticos, 2017 El artículo expone y analiza las fases de instrucción y de decisión por el obispo de las causas de nulidad matrimonial por el proceso breve. Se proponen diversos medios de prueba para practicar en la audiencia o sesión instructora, según los distintos ...
Cristina Guzmán Pérez
doaj
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source