Results 21 to 30 of about 239,296 (272)
About the Strength of Proof Statements in Judicial Decision: The Constitutive Leap [PDF]
, 2014 Este ensayo propone una crítica a la tesis pragmática según la cual los enunciados probatorios de las decisiones judiciales del tipo «está probado que p» poseen fuerza descriptiva siendo, por tanto, verdaderos o falsos.
Dei Vecchi, Diego
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Criterios de racionalidad en la aplicación del derecho
Revista de Derecho, 2022 Este artículo de investigación examina diversas propuestas generadas desde la filosofía del derecho y desde la teoría jurídica en torno a la exigencia de racionalidad no solo en la regulación del derecho, sino también en la adopción de las decisiones ...
PATRICIA RAQUEL MORRIS BOLAÑO +1 more
doaj +1 more source
Desnacionalización judicial de las personas dominicanas de ascendencia haitiana [PDF]
, 2014 Una sentencia reciente del Tribunal Constitucional de la República Dominicana, si fuera aplicada tal como está redactada, dejaría apátridas a miles de dominicanos y enviaría a otros Estados el mensaje de que las desnacionalizaciones arbitrarias masivas ...
Gamboa, Liliana, Harrington Reddy, Julia
core +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Freedom of Research and Impunity of Dictatorship: Constitutional Jurisprudence Adrift [PDF]
, 2019 Este trabajo parte de la evidencia de la impunidad de los crímenes de la dictadura franquista por obra, esencialmente, de un aparato judicial que ha bloqueado el acceso de las víctimas y de sus descendientes a la justicia.
Clavero Salvador, Bartolomé
core +2 more sources
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Advocatus, 2014 La promulgación de la Constitución Política de 1991 marcó en Colombia un cambio de paradigma Constitucional, demarcando grandes transformaciones para la ontología, axiología y metodología jurídica. Estas transformaciones se vislumbran en el
ANGÉLICA MARÍA REYES SÁNCHEZ
doaj +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source