Results 101 to 110 of about 7,036,429 (247)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Motor resonance and inhibitory mechanisms in action observation as revealed by corticospinal excitability

Scientific Reports
Motor resonance (MoR) refers to the automatic activation of motor circuits during action observation, reflecting an internal simulation of the observed movement.
Carlos Nieto-Doval, Aynur Ragimova, Gleb Perevoznyuk, Traian Popa, Oleg Shevtsov, Victoria Moiseeva, Matteo Feurra   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Social and creative decision making

, 2001
In this introductory chapter the authors summarize the chapters in the book by identifying and describing a number of dimensions on which the various chapters, and descriptions of decision making processes more generally, can be located. These dimensions
Allwood, Carl Martin,, Selart, Marcus, Lund University.   +2 more
core  

Translation and cultural adaption of Observer OPTION5 and OPTION12 in a Danish context

Health Literacy and Communication Open
Background and aim The aim of this study was to translate and culturally adapt the Observer scales OPTION5 and OPTION12 into Danish to improve the accessibility of the scales for all healthcare professionals and patients as co-researchers to objectively ...
Bettina Mølri Knudsen, Karina Olling, Karina Dahl Steffensen   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Affect and decision making: A ”hot” topic

, 2006
The seven papers in this special issue represent the breadth and complexity of approaches to the study of affect in judgment and decision processes. Four papers examine the role of arousal or specific emotions in decision making.
Slovic, P, Västfjäll, Daniel,, Peters, E, Gärling, Tommy,   +3 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Whoever wants better healthcare simply pays more: citizens' perception about voluntary private health insurance in Colombia

International Journal for Equity in Health
Objectives To explore the perceptions that Colombians have about voluntary private health insurance plans (VPHI) in the health system to identify the tensions that exist between the public and private systems.
Daniel Felipe Patiño-Lugo, Claudia Marcela Vélez, Diana Patricia Díaz-Hernández, Olga Francisca Salazar-Blanco, Juan Esteban González-Arango, Juan Carlos Velásquez-Correa, Leydi Camila Rodríguez-Corredor, Viviana María Vélez-Marín, Pamela Velásquez-Salazar   +8 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source