Results 211 to 220 of about 7,036,429 (247)

Support in Decision-Making for All. [PDF]

J Law Med Ethics
Gunkel J, Wasserman D, Francis L.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Self-produced signs in decision-making and contextual correlations. [PDF]

Front Psychol
Trieste L, Turchetti G.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Central neurocytomas: Decision-making process of postoperative treatment. Lesson learned. [PDF]

Neurosurg Rev
Corvino S, Corazzelli G, Di Nuzzo G, Seneca V, Granata R, De Paulis D, Cella M, Altieri R, Catapano G.   +8 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Practical recommendations for the implementation of shared decision-making in multiple myeloma care. [PDF]

PLoS One
Broekmans J, Schoefs E, Verbeke C, De Proost L, Ten Seldam S, Duncan E, Aviv A, Shoham V, Delforge M, Vanhellemont A, Huys I.   +10 more
europepmc   +1 more source

Supporting Decision Making in Early Years Initiatives: Co-Designing a Child Health Evidence Dashboard. [PDF]

Health Promot J Austr
Johnson BJ, Morgillo S, Hunter S, Perimal-Lewis L, Middleton G, Anderson J, Perry R, Eley S, Nori A, Wightman L, Taki S, Williams C, Brown V, Seidler AL, Hunter KE, Golley R.   +15 more
europepmc   +1 more source

The guidance ratio: a measure of post-diagnostic antibiotic decision-making. [PDF]

JAC Antimicrob Resist
Garpvall K, Aljundi A, Dahl A, Sterky E, Luthander J, Sütterlin S.   +5 more
europepmc   +1 more source

The influence of social cues in learning and decision-making over time. [PDF]

Front Psychol
Perez E, Shoenfelt A, Frazier I, El-Shafie D, Lin T, Lighthall NR, Ebner NC.   +6 more
europepmc   +1 more source