Results 151 to 160 of about 707,036 (345)

Identifying and Evaluating the Decision-Making Styles of Patients Referring to Specialty and Subspecialty Clinics in Iran

, 2020
Mehrdad Nasrollahzadehsabet, Mohammad Gholizadeh, Mohammad Faryabi   +2 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Hunting the Best Opportunity Through the Arrow of General Decision-Making Styles: Unfolding the Role of Social Capital and Entrepreneurial Intention. [PDF]

Front Psychol, 2022
Hong J, Gill SA, Javaid H, Ali Q, Murad M, Shafique M.   +5 more
europepmc   +1 more source

New service development in high tech sectors: a decision making perspective [PDF]

Many service companies active in high tech sectors have implemented largely decentralized decision architectures in their innovation processes. This is done to improve responsiveness under extremely dynamic and uncertain business conditions.
Lievens,Annouk, Riel,Allard C.R.,van
core   +1 more source

Influence of Family Structure on Consumer Decision-making Style in Iran

, 2011
Kambiz Heidarzadeh Hanzaee, Fereshteh Lotfizadeh   +1 more
openalex   +2 more sources

FEATURES OF DECISION MAKING AND SUSTAINABILITY IN THE ORGANIZATION AMONG EMPLOYEES WITH DIFFERENT TYPES OF COGNITIVE STYLE OF PERSONALITY: FIELD DEPENDENCE AND FIELD INDEPENDENCE

, 2021
A.Yu. Tishchenko, I.M. Ushakova, Tetiana Seliukova   +2 more
openalex   +1 more source

Decision-making Styles in Adolescent Offenders and Non-offenders: Effects of Emotional Intelligence and Empathy [PDF]

, 2021
Arcadio de Jesús Cardona-Isaza, Saray Velert Jiménez, Inmaculada Montoya‐Castilla   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source