Results 111 to 120 of about 5,616,889 (295)
Climate Change Impacts, Vulnerabilities, and Adaptation in Northwest Alaska [PDF]
, 2006 16 pagesA two-day workshop on climate change impacts, vulnerabilities and adaptation in northwest Alaska was held in Kotzebue on May 24 & 25. The overall objective of the workshop was to help key stakeholders in northwest Alaska consider climate change
Failing, Lee +2 more
core +1 more source
The Modeling of the Decisional Process A Case of Study for the Portfolio Management [PDF]
Informatică economică, 2007 In the architecture of the management functionality and performance, its decisional component has a privileged position. No other element has a more stressed managerial specificity and a greater impact in all the plans of its activities and results ...
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
a synthesis of interdisciplinary research on climate, water, and decision-making under uncertainty [PDF]
, 2013 : The Decision Center for a Desert City at Arizona State University—funded by the National Science Foundation since 2004—conducts research relevant to water resources and urban climate dynamics under multiple uncertainties.
core
Sign Theory: A Non-extensional Theory of Preference [PDF]
, 2003 57 pagesA non-extensional theory of preference, called Sign Theory, is proposed and tested. Sign Theory considers preference construction as an evidence-building process, in which local valuation of evidence combines additively to form a global judgment.
Lin, Shuyeu, Slovic, Paul
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
THE DECISIONAL TRANSPARENCY IN PUBLIC ADMINISTRATION [PDF]
Challenges of the Knowledge Society, 2011 The principle of decisional transparency is one of the principles of good administration, fundamental principles of public administration and it is enshrined in the law of many European Union member states, including our country. In their work the public
OCTAVIA MARIA CILIBIU
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source