Results 141 to 150 of about 5,616,889 (295)

Decisions, decisions, decisions

open access: yes, 2009
Cells must perpetually decide on three big choices in life: to grow, to divide or to die. These system-level decisions are the output of a complex and still very poorly understood molecular algorithm, which is built from many different sub-routines. Biochemical and genetic insights, sometimes coupled with good fortune, have illuminated key individual ...
Tyers, Mike, Amon, Angelika B
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

ОБҐРУНТУВАННЯ ВИБОРУ МЕТОДУ ЦІЛЬОВОГО ПРОГРАМУВАННЯ ДЛЯ ОПТИМІЗАЦІЇ СКЛАДУ ПАРКУ СПЕЦІАЛЬНИХ ТАНСПОРТНИХ ЗАСОБІВ

open access: yesSučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2013
Метою даної статті є представлення результатів особистих досліджень автора по обгрунтованого вибору методу багатокритеріальної оптимізації складу парку транспортних засобів відділів прикордонної служби на основі використання специфічної додаткової ...
Mykola P. Hashchuk, Oleh V. Skrypkar
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Project completion report for study of the effectiveness and impact of the Oregon minimum deposit law

open access: yes, 1974
prepared by Applied Decision Systems and Decision Making Information."Presented to Oregon Legislative Fiscal Officer and Department of Transportation, Oregon Division of Highways."Covers OCLC #1343955200 and OCLC #1343955176.This archived document is ...

core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy