Results 171 to 180 of about 7,021,374 (331)

Surrogate Endpoints in Regulatory Decision-Making. [PDF]

Clin Transl Sci
Jeng LJB, Siegel J.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Decision Making in Pediatric Heart Failure and Transplant: A Qualitative Analysis of Parental Decision Making. [PDF]

Pediatr Transplant
Phillips KA, Lancaster E, Tuckett S, Galyean P, Zickmund SL, Molina KM, Pinto NM, Ozanne EM.   +7 more
europepmc   +1 more source

The changing decision-making narratives in 25 years of TEN-T policies

, 2017
Ángel Aparicio
openalex   +1 more source

Digitizing the public administration and safeguarding individual rights: automated decision-making at the intersection of the GDPR and Polish administrative procedure

, 2021
Filip Geburczyk
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Differential Effects of Kinesthetic and Visual Motor Imagery Perspectives on Corticospinal Excitability in Healthy Adults

Brain Stimulation
Gleb Perevoznyuk, Ainur Ragimova, Artyom Batov, Aleksandra Pleskovskaya, Anthony Mensah, Daria Ponomareva, Matteo Feurra   +6 more
doaj   +1 more source

Clinical Decision-Making Case: Intussusception. [PDF]

J Educ Teach Emerg Med
Milman B, Parnell S.
europepmc   +1 more source

Decision-Making Support in Resource Management in Manufacturing Scheduling

, 2018
Nafissa Yussupova, Dmitry Rizvanov
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source