Results 201 to 210 of about 4,134,598 (285)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Study on the Diagnostic Value of Clinical Decision Rules for Malignant Tumors Complicated with Pulmonary Thromboembolism: A Retrospective Analysis. [PDF]

Clin Appl Thromb Hemost
Yang J, Wang H, Han J, Zhang L, Ma H, Liu X, Li C, Chen H, Zhang H, Fei J.   +9 more
europepmc   +1 more source

Decision rules for egg-color-based rejection by two cavity-nesting hosts of the brown-headed cowbird.

J Exp Biol, 2023
Di Giovanni AJ, Villa J, Stanback MT, Thompson CF, Sakaluk SK, Hauber ME, Hanley D.   +6 more
europepmc   +1 more source

Decision Rule [PDF]

, 2020
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A cross-sectional analysis of four common clinical decision rules for pulmonary embolism, Mashhad, Iran. [PDF]

J Cardiovasc Thorac Res
Hassani S, Najaf Najafi N, Khodadadi A, Gandomi F, Amini M.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Fusing Diverse Decision Rules in 3D-Radiomics for Assisting Diagnosis of Lung Adenocarcinoma. [PDF]

J Imaging Inform Med
Ren H, Wang Q, Xiao Z, Mo R, Guo J, Hide GR, Tu M, Zeng Y, Ling C, Li P.   +9 more
europepmc   +1 more source

DECISIONS AND RULINGS [PDF]

The Bulletin of the National Tax Association, 1918
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source