Results 51 to 60 of about 308,520 (290)

Decision Tree Ensemble Method for Analyzing Traffic Accidents of Novice Drivers in Urban Areas

open access: yesEntropy, 2019
Presently, there is a critical need to analyze traffic accidents in order to mitigate their terrible economic and human impact. Most accidents occur in urban areas.
Serafín Moral-García   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The use of rough rules in the selection of topographic objects for generalizing geographical information

open access: yesPolish Cartographical Review, 2020
Selection is a key element of the cartographic generalisation process, often being its first stage. On the other hand it is a component of other generalisation operators, such as simplification.
Fiedukowicz Anna
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Neural Named Entity Recognition and Multi-Type Normalization Tool for Biomedical Text Mining

open access: yesIEEE Access, 2019
The amount of biomedical literature is vast and growing quickly, and accurate text mining techniques could help researchers to efficiently extract useful information from the literature.
Donghyeon Kim   +8 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pengenalan Aksara Jawi Tulisan Tangan Menggunakan Freemen Chain Code (FCC), Support Vector Machine (SVM) dan Aturan Pengambilan Keputusan

open access: yesJurnal Nasional Teknik Elektro, 2016
Jawi is one variant of Arabic script consists of 35 characters. Some of Jawi characters have the same main shape, but different number of dots in different location.
Safrizal, Fitri Arnia, Rusdha Muharar
doaj   +1 more source

Decision Rules Construction: Algorithm Based on EAV Model

open access: yesEntropy, 2020
In the paper, an approach for decision rules construction is proposed. It is studied from the point of view of the supervised machine learning task, i.e., classification, and from the point of view of knowledge representation.
Krzysztof Żabiński, Beata Zielosko
doaj   +1 more source

Home - About - Disclaimer - Privacy