Results 91 to 100 of about 6,642,537 (325)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Dynamic room pricing model for hotel revenue management systems

Egyptian Informatics Journal, 2011
This paper addresses the problem of room pricing in hotels. We propose a hotel revenue management model based on dynamic pricing to provide hotel managers with a flexible and efficient decision support tool for room revenue maximization.
Heba Abdel Aziz, Mohamed Saleh, Mohamed H. Rasmy, Hisham ElShishiny   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

An overview of CBDCs and their potential role in the green economy [version 1; peer review: 1 approved, 2 approved with reservations]

Open Research Europe
In recent years, there has been an ever-intensifying discussion around the use and establishment of Central Bank Digital Currencies (CBDC) in the global economy.
Konstantinos Alexakis, Vangelis Marinakis, Paanagiotis Kokkinakos, Christos Kontzinos, Fotis Siouzos, Maria Flouri   +5 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The extent and type of use, opportunities and concerns of ChatGPT in community pharmacy: A survey of community pharmacy staff

Exploratory Research in Clinical and Social Pharmacy
Background: Since the widespread availability of Chat Generative Pre-Trained Transformer (ChatGPT), the public is confronted with accessible artificial intelligence tools.
Emma Janske de Ruiter, Vesna Maria Eimermann, Claudia Rijcken, Katja Taxis, Sander Diederik Borgsteede   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Accuracy is Not Enough: Multi-Head Gated Attention Multiple Instance Learning Model for Explainable Breast Cancer Diagnosis

IEEE Access
Attention-based models are inherently interpretable owing to their ability to highlight relevant features, yet their explanations are rarely rigorously validated.
Jakub Buler, Rafal Buler, Maciej Bobowicz, Michal Grochowski   +3 more
doaj   +1 more source

Clinical decision support systems

Swiss Medical Weekly, 2014
Clinical decision support (CDS) systems link patient data with an electronic knowledge base in order to improve decision-making and computerised physician order entry (CPOE) is a requirement to set up electronic CDS. The medical informatics literature suggests categorising CDS tools into medication dosing support, order facilitators, point-of-care ...
Beeler Patrick Emanuel, Bates David Westfall, Hug Balthasar Luzius   +2 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source