Results 231 to 240 of about 21,698,220 (290)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The Evolution of CT-Based Robotic Systems in Total Knee Arthroplasty: From Precision Tools to Intelligent Surgical Partners. [PDF]

J Orthop Case Rep
Aneja K, Machaiah PK, Shyam A.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Artificial intelligence in clinical trials-state of the evidence, gaps, and next steps. [PDF]

EClinicalMedicine
Armoundas AA, Tarabanis C, Loscalzo J.
europepmc   +1 more source

From Evidence to Value: Integrating Evidence-Based Medicine, Patient Safety, Quality Improvement, Learning Health Systems, and Value-Based Healthcare. [PDF]

J Eval Clin Pract
Okabayashi T, Inada R, Imai T, Ozaki K, Hayashi K.   +4 more
europepmc   +1 more source

State of the industry: integration of 3Rs principles and new approach methodologies in non-clinical product development through fit-for-purpose. [PDF]

Front Med (Lausanne)
Poppenborg SM, Webster DA, Carlsson B.
europepmc   +1 more source

Human factors and airway management: focus on the Swiss Airway Guidelines. [PDF]

Front Med (Lausanne)
Balmer C, Casso G, Schoettker P, Savoldelli GL.   +3 more
europepmc   +1 more source

Artificial intelligence-driven risk prediction of polypharmacy in older adults: current advances, clinical applications, and future perspectives. [PDF]

Front Public Health
Chen J, Tao L.
europepmc   +1 more source

Early Risk Stratification of Severe Trauma in the Emergency Department: Integrating Clinical Scoring Systems, Dynamic Biomarkers, and Artificial Intelligence-A Narrative Review. [PDF]

Ther Clin Risk Manag
Sun X, Han J, Ni J, Shen Y.
europepmc   +1 more source