Conversion between the Brief assessment of Impaired Cognition, Brief Assessment of Impaired Cognition Questionnaire, and Mini-Mental State Examination in a mixed clinical sample. [PDF]
Jørgensen K +8 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Bringing Regulatory-Style Benefit-Risk Assessment to the Bedside: A Structured Evidence Synthesis Methodology for Shared Decision-Making. [PDF]
Garcia-Zamora S +3 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
2026-2027 AAFP Immunization Schedules: What's New and Why It Matters For Family Medicine. [PDF]
Savoy M.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Retraction of "Discoloration of teeth due to different intracanal medicaments" published in Restorative Dentistry and Endodontics. [PDF]
europepmc +1 more source
Coagulopathy in Critically Ill Patients With Sepsis: Protocol for a Scoping Review. [PDF]
Andersen CHS +6 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Decision Tree Model for Predicting the Overall Survival of Endometrial Cancer Patients with Adenomyosis. [PDF]
Cecen Donmez Y +8 more
europepmc +1 more source

