Results 191 to 200 of about 686,580 (270)

Comprehensive Characterization of the Immune Microenvironment Based on Nested Resampling Machine Learning Framework Identifies TRAF3 Interacting Protein 3 as a Promising Regulator to Improve the Resistance to Immunotherapy in Glioma

open access: yesAdvanced Science, EarlyView.
This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang   +15 more
wiley   +1 more source

Brain‐Inspired Polymer Dendrite Networks for Morphology‐Dependent Computing Hardware

open access: yesAdvanced Science, EarlyView.
Although process variability is often perceived as a drawback in electronics, this work harnesses the stochastic nature of electropolymerization as a powerful ally for computation. The resulting conductive polymer dendrites exhibit unique structure‐property relationships and support in memory computing, paving the way for the development of a new class
Corentin Scholaert   +3 more
wiley   +1 more source

Drug Resistance Predictions Based on a Directed Flag Transformer

open access: yesAdvanced Science, EarlyView.
 CAPTURE, a deep learning framework combining structural and sequence data to predict drug‐resistant Mpro mutations, revealing that PAXLOVID use may be accelerating resistance—supporting real‐time viral surveillance and therapeutic design. Abstract The evolving SARS‐CoV‐2 virus threatens global public health, particularly with potential resistance to ...
Dong Chen   +8 more
wiley   +1 more source

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

open access: yesAdvanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai   +8 more
wiley   +1 more source

Predictive modeling of oil rate for wells under gas lift using machine learning. [PDF]

open access: yesSci Rep
Ma F   +11 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy