Results 201 to 210 of about 741,105 (343)

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Learning decision trees from dynamic data streams

, 2005
João Gama, Pedro Medas, Pedro Rodrigues
openalex   +1 more source

Adaptive Exact Learning of Decision Trees from Membership Queries [PDF]

, 2019
Nader H. Bshouty, Catherine A. Haddad-Zaknoon   +1 more
openalex   +1 more source

Cost-Sensitive Decision Tree Learning [PDF]

2019 Amity International Conference on Artificial Intelligence (AICAI), 2019
openaire   +1 more source

Multivariate decision trees for machine learning

, 2020
ÖZET Bu tezde, tek değişkenli, doğrusal, ve doğrusal olmayan çok değişkenli karar ağaç kurma metodlan karşılaştırıldı. Tek değişkenli karar ağaçları için örnek olarak ID3, çok değişkenli karar ağaçlan için CART yöntemi kullanıldı. Doğrusal ve doğrusal olmayan metodlar içinse karar düğümünde değişik sinir ağlan yapılarından faydalanıldı.
openaire   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Flight delay prediction: Evaluating machine learning algorithms for enhanced accuracy. [PDF]

PLoS One
AlBassam SAA, AlShahrani DN.
europepmc   +1 more source

GradTree: Learning Axis-Aligned Decision Trees with Gradient Descent

Sascha Marton, Stefan Lüdtke, Christian Bartelt, Heiner Stuckenschmidt   +3 more
openalex   +2 more sources

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Integrating Numerical Data with AI-Based Image Processing Techniques to Improve the Diagnostic Accuracy of Detecting Dental Caries in Panoramic Radiographs. [PDF]

Diagnostics (Basel)
Başarı B, Ulusoy N, Dimililer K.
europepmc   +1 more source