Results 111 to 120 of about 1,389 (206)

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type
Carlos Ceron   +22 more
wiley   +1 more source

Efficacy of Low‐Dose Naltrexone in Women With Fibromyalgia Syndrome: A 12‐Month Randomised, Double‐Blind, Placebo‐Controlled Single‐Centre Clinical Trial (INNOVA Study)

open access: yesEuropean Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Low‐dose naltrexone (LDN) has been used off‐label for fibromyalgia syndrome (FMS) for over a decade, supported by small crossover trials. The INNOVA study evaluated the safety and efficacy of LDN 4.5 mg versus placebo on pain intensity over 12 months in women with FMS.
Carla Rodríguez‐Freire   +7 more
wiley   +1 more source

Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis: A shared phenotype across brain‐expressed sodium channelopathies

open access: yesEpilepsia, Volume 67, Issue 7, Page 3629-3643, July 2026.
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli   +43 more
wiley   +1 more source

Impact of Pharmacist Board Certification on Health Outcomes of Critically Ill Patients: An Analysis of the Optimizing Pharmacist‐Team Integration for ICU Patient Management (OPTIM) Study

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.
ABSTRACT Background Critical care pharmacists (CCPs) reduce adverse drug events (ADEs) and mortality in the intensive care unit (ICU). Board certification is the established professional standard for CCPs, but its impact on ICU patient outcomes, including its relationship between CCP characteristics and workload, remains unclear.
Susan E. Smith   +197 more
wiley   +1 more source

Aspectos críticos del empleo en salud de modelos estadísticos de clasificación

open access: yesRevista Médica Electrónica, 2014
Los modelos estadísticos de clasificación se emplean cotidianamente en salud como sistemas de evaluación que permiten construir grupos homogéneos en la ayuda de pronósticos, diagnósticos, elección de terapias y cuantas situaciones requieran la ...
Vielka González Ferrer
doaj  

Adaptation of the International Consortium for Health Outcomes Measurement Standard Set for Inflammatory Bowel Disease for Routine Collection in Clinical Practice

open access: yesJCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT Background and Aims Value‐based healthcare (VBHC) is based on evaluating clinical interventions according to their ability to improve outcomes and costs to finally enhance quality of care. As part of an initiative to introduce VBHC in inflammatory bowel disease (IBD), our project aimed to adapt the International Consortium for Health Outcomes ...
Xavier Calvet   +33 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri   +26 more
wiley   +1 more source

Calidad de vida en enfermos crónicos

open access: yesRevista Habanera de Ciencias Médicas, 2007
La Psicología de la Salud ha contribuido a un enfoque más humanizado e integral en el estudio y tratamiento de las enfermedades crónicas. La calidad de vida y, en especial, la calidad de vida relacionada con la salud, se han convertido en una de las ...
Carmen Regina Victoria García-Viniegras   +1 more
doaj  

Person‐Centered Care Planning for People With Multiple Chronic Conditions: An Environmental Scan of Models and Approaches

open access: yesLearning Health Systems, Volume 10, Issue 3, July 2026.
ABSTRACT Introduction Person‐centered care planning (PCCP) involves active collaboration between people seeking care, clinical teams, and others to co‐create longitudinal treatment plans. It is a crucial part of care for people with multiple chronic conditions (MCCs) and other complex needs.
Annette M. Totten   +9 more
wiley   +1 more source

Challenging Patterns of Fine‐Scale Genetic Structure in Galicia and East‐to‐West Genetic Divergence Across the Iberian Peninsula—When Technical Batches Rewrite History

open access: yesFASEB BioAdvances, Volume 8, Issue 7, July 2026.
Findings reported by Bycroft et al. [1] for the Iberian Peninsula, including ultra‐fine population structure in Galicia, East–West genetic differentiation, and North African ancestry associated with the ‘Reconquista’ period, may be influenced by technical artifacts and sampling limitations within the EPICOLON Phase I dataset.
Jacobo Pardo‐Seco   +4 more
wiley   +1 more source
medicine
ra1-1270
public aspects of medicine
salud pública
toma de decisiones
covid-19
3. good health
medicine general
r5-920
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