Results 111 to 120 of about 1,697,394 (313)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Balfour Declaration

open access: yes, 2016
After the "The McMahon-Hussein correspondence: phase one of the partition process" and "The Sykes-Picot agreements – phase two of the partition process", this article is the sequel of the roundup, presenting The Balfour Declaration, in context and ...
Guediri, Kaoutar
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Ilisu Dam in Turkey and the Role of Export Credit Agencies and NGO Networks

open access: yesWater Alternatives, 2010
The World Commission on Dams (WCD) report focused attention on the question of how those displaced by large dams can be adequately compensated and properly resettled. An important debate from the Dams and Development Forum concerned the appropriate roles
Christine Eberlein   +3 more
doaj  

Declare, declare! [PDF]

open access: yesThe Psychiatrist, 2010
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

PARTICULAR CONSTITUTIONAL AND LEGAL FACETS OF THE PROBLEM OF INTERACTION BETWEEN THE STATE AND AN INDIVIDUAL WITHIN THE SCOPE OF HUMAN RIGHTS PROTECTION

open access: yesВестник Кемеровского государственного университета, 2014
Within the framework of the issue being researched, the author of the paper considers extremely significant the fact that as a result of enactment of the core historic legal acts an individual becomes independent and the State abstains from interference ...
E. Yu. Balayan
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Declaration du comite Ad Hoc de l'OUA sur l'Afrique Australe relative a la question de l'Afrique du sud

open access: yes, 1989
Declaration of the OAU AD-HOC Committee on Southern Africa on the question of South Africa. (1989-09), Harare, Zimbabwe 21 August 1989 during the 48th Session of the ACP Council of Ministers on 27 October 1989 in ...

core  

“Towards Greater Unity and Integration through Shared Values” [PDF]

open access: yes, 2011
16th Ordinary Session of the ...
African Union
core  

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