Results 141 to 150 of about 197 (187)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Liberia: 2001 Article IV Consultation and Overdue Financial Obligations to the Fund--Review Following Declaration of Ineligibility--Staff Report; Public Information Notice on the Executive Board Discussion; and Statement by the Executive Director for Liberia

IMF Staff Country Reports, 2002
openaire   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

An argument addressed to the yeomanry of Ireland, demonstrating the right, the propriety, the utility, and the obligation of declaring their sentiments on political subjects, in their public distinctive character of yeomen

openaire   +1 more source

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Programming Normative Artifacts with Declarative Obligations and Prohibitions

2009 IEEE/WIC/ACM International Joint Conference on Web Intelligence and Intelligent Agent Technology, 2009
Abstract—Normative concepts (e.g., obligations and prohibitions) are seen as a suitable tool for regulating the observable behavior of software agents. An enforcement mechanism – a process that detects when a norm is active, detects violations of the norms and handles these violations – is crucial for the practical use of norms in the construction of ...
Leendert Van Der Torre
exaly   +3 more sources

From Declarations to Measurable Obligations: The Evolution of Non-Regression Provisions in the Protection of Foreign Investments

RU SCIENCE, 2023
1. Wettstein, F. K. International business and human rights: A research agenda / F. Wettstein, E. Giuliani, G. D. Santangelo, G. K. Stahl // Journal of World Business. – 20199. – No. 54 (1). – P. 54-65.
openaire   +1 more source

From declared asset retirement obligations to a decommissioning cost estimate for onshore crude oil fields in Nigeria

Journal of Environmental Management, 2017
As in most mature crude oil producing regions, asset divestment has commenced in Nigeria. Decommissioning and associated environmental liabilities are expected to become important problems requiring attention. Public and government engagement on decommissioning will be ineffective without information on cost of decommissioning liabilities, which are ...
Erovie-Oghene U, Afieroho, Shirish L, Patil, Abhijit, Dandekar, Robert, Perkins, Douglas, Reynolds   +4 more
openaire   +2 more sources

Interpreting the declaration of Helsinki (2008): "must", "should" and different kinds of obligation.

Medicine and law, 2011
The Declaration of Helsinki is widely regarded as the preeminent code of research ethics. Revised six times since 1964, the versions differ in their substantive requirements, and also in the way that obligations are expressed, especially regarding the use of the prescriptors "should" and "must".
H, Schmidt, S, Mehring, J, McMillan
openaire   +1 more source