Results 241 to 250 of about 90,677 (316)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

The Heidelberg Functional Foot Model-Application to Cavovarus and Equinovarus Feet. [PDF]

J Foot Ankle Res
Campos S, Salami F, Chen Q, Putz C, Tsitlakidis S, Wolf SI.   +5 more
europepmc   +1 more source

Spatiotemporal computations in the insect celestial compass. [PDF]

Nat Commun
Gkanias E, Webb B.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Talar Neck Osteotomy for Treating Neurologic Cavovarus Foot in an Adult: A Case Report. [PDF]

Cureus
Moriwaki D, Nakasa T, Ikuta Y, Sakurai S, Adachi N.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission. [PDF]

Space Sci Rev
Christian ER, Mitchell JG, Bruno A, Albaijes D, Bailey Newman S, Boggs RC, Choi MK, Cohen CMS, Cook WR, Darwish YS, Davis AJ, de Nolfo GA, Dumonthier JJ, Garnett RD, Gkioulidou M, Gregory KJ, Guzman Garcia D, Haas JP, Hollenhorst C, Jeunon M, Kaiser MA, Kanekal SG, Kecman B, Leske RA, Letzer JD, Liceaga Indart I, McComas DJ, McNeel B, Muro GD, Nolan JT, Ogindo M, Petrowich P, Reaves WJ, Rosnack TP, Saghafi N, Salerno CL, Schwadron NA, Silber MA, Smith ES, Smith MT, Suárez G, Tatoli T, Tiu CP, Wiedenbeck ME, Windhausen MH, Xu Z.   +45 more
europepmc   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Clinical efficacy of novel biogenically fabricated titania nanoparticles enriched mouth wash in treating the tooth dentine hypersensitivity: A randomized clinical trial. [PDF]

Pak J Med Sci
Mansoor A, Mansoor E, Hussain K, Khan S.
europepmc   +1 more source