Results 121 to 130 of about 15,519 (321)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

La resistenza ebraica nella storiografia israeliana in lingua inglese. Un breve profilo

open access: yesDiacronie. Studi di Storia Contemporanea
The article examines studies on Jewish resistance in Israeli historiography on the Shoah. Through the analysis of various contributions, conference proceedings, articles and monographs, the article aims to reconstruct an essential historiographical ...
Felice FERRARO
doaj  

Exhibited Thoughts of Architecture

open access: yesMuseum, Materials and Discussions
In recent decades, architecture exhibitions have become the subject of a specific study, as corroborated by the international diffusion of conferences and publications dedicated to this theme.
Anna Rosellini
doaj   +1 more source

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

Documentation for the machine-readable version of the Henry Draper Catalogue (edition 1985) [PDF]

open access: yes
An updated, corrected and extended machine-readable version of the catalog is described. Published and unpublished errors discovered in the previous version was corrected; letters indicating supplemental stars in the BD have been moved to a new byte to ...
Roman, N. G., Warren, W. H., Jr.
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

ASSESSMENTS OF AUTOANTIBODY AND CYTOKINE CONTENTS IN TEENAGERS OF INDUSTRIAL CENTERS SCREENING EXAMINATION

open access: yesActa Biomedica Scientifica, 2012
270 teenagers without acute inflammation signs at the moment of the examination living in the industrial centers of Eastern Siberia have been examined.
L. B. Masnaviyeva, I. V. Kudayeva
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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