Results 41 to 50 of about 5,365,252 (221)

Declining Discount Rates: Evidence from the UK [PDF]

open access: yes
We estimate schedules of declining discount rates for cost benefit analysis in the UK. We highlight the importance of model selection for this task and hence for the evaluation of long-term investments, namely climate change prevention and nuclear build ...
Ekaterini Panopoulou   +3 more
core  

Optimal Rotation under Continually – or Continuously – Declining Discount Rate [PDF]

open access: yes, 2017
It has been argued from a number of perspectives that the discount rate might decline with increasing period of discounting. With a stepped profile of decline, financially optimal rotations are quite likely to occur at a few discrete ages.
Price, Colin
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

The Information Content of German Discount Rate Changes [PDF]

open access: yes
Discount rate changes always receive considerable attention in financial markets. Two hypotheses compete to explain financial market reactions: the direct ‘borrowing cost effect’ and the announcement effect.
Manfred J.M. Neumann, Jens Weidmann
core  

Trustworthy Multimodal Attention Framework for Creep Rupture Life Prediction Under Data‐Scarce Conditions: A Case Study on IN718

open access: yesAdvanced Science, EarlyView.
An attention‐based multimodal deep learning framework is developed to predict the creep life of Ni‐based superalloys by fusing processing parameters with microstructural micrographs. The model achieves high accuracy (R2 = 0.92), aligns with metallurgical principles by capturing δ‐phase influence, and incorporates uncertainty quantification, offering a ...
Haopeng Lv   +10 more
wiley   +1 more source

Properties of the Social Discount Rate in a Benthamite Framework with Heterogeneous Degrees of Impatience [PDF]

open access: yes
This paper derives the properties of the discount rate that should be applied to a public-sector project when the affected population has heterogeneous degrees of impatience.
Elyès Jouini   +2 more
core  

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Determining the Discount Rate for Government Projects [PDF]

open access: yes
Discount rates are widely used in the public sector to assess policy proposals where costs and benefits accrue over long time periods. Socially optimal policy choices require an appropriate choice of discount rate.
Louise Young
core  

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

open access: yesAdvanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu   +3 more
wiley   +1 more source

A social discount rate for Turkey [PDF]

open access: yes
ocial Discount Rate (SDR) is a very crucial policy parameter in public project appraisals due to its resource allocation impacts. This study estimates an SDR for Turkey using the Social Time Preference Rate (STPR) approach. The elasticity of the marginal
Halicioglu, Ferda, Karatas, Cevat
core  

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