Results 191 to 200 of about 19,228 (290)

Serum Urate and Renal Dysfunction: Bidirectional Genetic Associations, External Validation, and Exploratory Multi-Omics Characterization of Antithrombin (SERPINC1) in Hyperuricemic Nephropathy. [PDF]

Genes (Basel)
Jin L, Wang F.
europepmc   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

Central complex representations of self-movement are sufficient to compute wind direction in flight. [PDF]

Sci Adv
May CE, Cellini B, Stupski SD, Lopez AP, Mangat N, van Breugel F, Nagel KI.   +6 more
europepmc   +1 more source

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan, Yuewei Li, Chao Mi, Zhengwen Yang, Lana McClements, Steven J. Langford, Jiayan Liao   +6 more
wiley   +1 more source

Letter to the Editor: Artificial wisdom and the transience of truth: Ethical and temporal reflections on artificial intelligence-human inquiry into history. [PDF]

World J Methodol
Panda PK.
europepmc   +1 more source

Generative AI‐Enabled Discovery and Experimental Demonstration of Ultra‐Broadband Epsilon‐Near‐Zero Perfect Absorbers

Advanced Science, EarlyView.
Researchers developed and applied a generative artificial intelligence (AI) model to optimize epsilon‐near‐zero thin film stacks for ultra‐broadband perfect absorption of light. The fabricated AI‐designed absorber, with a total thickness of only 160 nm, experimentally demonstrated an absorption bandwidth exceeding 1000 nm while maintaining greater than
David Dang, Meena Salib, Quynh Dang, Sudip Gurung, Juan Calixto, Xuguo Zhou, Stuart Love, Massee Akbar, Aleksei Anopchenko, Wilton J.M. Kort‐Kamp, Ho Wai Howard Lee   +10 more
wiley   +1 more source

A Projector-Based Augmented-Reality Localization Device for Breast-Conserving Surgery: Phantom Pipeline and End-to-End Error Budget. [PDF]

Bioengineering (Basel)
Gong X, Heng J, Feng H, Zhang S.
europepmc   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source

Multiplexed encoding of frequency-modulated sweep features in the inferior colliculus. [PDF]

J Neurophysiol
Drotos AC, Wajdi SZ, Malina M, Silveira MA, Williamson RS, Roberts MT.   +5 more
europepmc   +1 more source

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

Advanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou, Zhuo Chang, Xianjun Wu, Sijie Wang, Yuzhi Zhang, Hao Zhang, Haoyu Xu, Ruining Peng, Zhe Wang, Huiyun Xu, Yu Liu, Guangkui Xu, Nu Zhang, Hui Yang   +13 more
wiley   +1 more source