MolMiner: Toward Controllable, Three‐Dimensional‐Aware, Fragment‐Based Molecular Design
MolMiner is a fragment‐based, geometry‐aware, and order‐agnostic generative model for molecular design with strong inductive biases. Using symmetry‐aware fragment assembly, dynamic three‐dimensional geometry, and multi‐property conditioning, MolMiner enables interpretable and controllable molecular generation.
Raul Ortega‐Ochoa +2 more
wiley +1 more source
Integrative multiomics analysis identifies RARRES2 as a regulator of keloid pathogenesis through STAT3/HSPG2 signaling axis. [PDF]
Luan W +5 more
europepmc +1 more source
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang +9 more
wiley +1 more source
Identification of therapeutic targets for insomnia through genetic and plasma proteomic approaches. [PDF]
Wang X, Lu J, Lin F, Li G, Zhao W.
europepmc +1 more source
Solving Data Overlapping Problem Using A Class‐Separable Extreme Learning Machine Auto‐Encoder
The overlapping and imbalanced data in classification present key challenges. Class‐separable extreme learning machine auto‐encoding (CS‐ELM‐AE) is proposed, which is an enhancement of ELM‐AE that better handles overlapping data by clustering points from the same class together. Applying oversampling addresses imbalanced data.
Ekkarat Boonchieng, Wanchaloem Nadda
wiley +1 more source
Integrated multi-omics reveals the ITGB2-IL2RB-NK axis in promoting papillary thyroid carcinoma progression and immune microenvironment crosstalk. [PDF]
Xu J, Gao C.
europepmc +1 more source
Towards Advanced Intelligent and Perceptive Soft Grippers
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim +4 more
wiley +1 more source
IRS-Assisted Dual-Mode Relay-Based Adaptive Transmission. [PDF]
Wang D +5 more
europepmc +1 more source
Ag/Ag2S Nanoparticle‐Based In‐Materio Lightweight Cryptographic System for IoT Edge Security
This work presents a nanomaterial‐based in materio encryption method that directly transforms analog signals through nonlinear Ag/Ag2S nanoparticle networks. By exploiting the inherently nonuniform characteristics that arise from random arrangement of nanoparticles as a unique security key, the approach produces highly complex encrypted waveforms ...
Hiroki Tabata +7 more
wiley +1 more source
DECODE VRL Report No. 1: Lymphocyte Survival After Diagnostic Vitrectomy - Does Size Matter? [PDF]
Kowalski M +9 more
europepmc +1 more source

