Results 81 to 90 of about 12,636 (259)

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

Performance analysis of ultra-reliable short message decode and forward relaying protocols

open access: yesEURASIP Journal on Wireless Communications and Networking, 2018
Machine-type communication (MTC) is a rapidly growing technology which covers a broad range of automated applications and propels the world into a fully connected society.
Parisa Nouri   +2 more
doaj   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

open access: yesAdvanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong   +10 more
wiley   +1 more source

Space Diversity-Based Hybrid Decode Amplify and Forward Cooperative Relay Protocol

open access: yesABUAD Journal of Engineering Research and Development
In today's wireless communication systems, ensuring secure and reliable data transmission is essential due to the increasing complexities of eavesdropping techniques and the demand for improved signal delivery.
Job Adedamola Adeleke, Opeyemi Oyelaran
doaj   +1 more source

Secrecy Performance Analysis of Relay Selection in Cooperative NOMA Systems

open access: yesIEEE Access, 2019
This paper investigates the security performance of two relay selection schemes for cooperative non-orthogonal multiple access (NOMA) systems, where K randomly distributed relays are employed with either decode-and-forward (DF) or amplify-and-forward (AF)
Zhenling Wang, Zhangyou Peng
doaj   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

Adaptive AF/DF Selection With FD/HD Switching in Two-Way Relay Networks

open access: yesIEEE Access, 2017
The full-duplex (FD) and two-way relay are promising techniques for their high spectrum efficiency. However, the incompletely self-interference cancellation may reduce the performance gain of two-way relay networks, which operates in FD mode.
Quanqiang Miao, Bo Bai, Wei Chen
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

open access: yesAdvanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy