Results 121 to 130 of about 19,327 (236)

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

Latent Diffusion Process With Mechanistic Guidance For Designing Functionally Graded Metamaterials With Perfect Connectivity

open access: yesAdvanced Science, EarlyView.
A latent diffusion‐based framework is proposed for designing functionally graded metamaterials with perfect connectivity. By integrating vector‐quantized latent representations with mechanistic guidance, the framework enables accurate inverse design toward target elastic properties.
Jongbin Yu, Dosung Lee, Namjung Kim
wiley   +1 more source

Partial decode-forward in relay networks

open access: yes, 2014
Cooperative transmission acts as a distributed solution for providing robust wireless communications. It pools available resources, such as power and bandwidth, across the network.
Tang, Yao
core  

CoSP: Reconfigurable Metamaterial Inverse Design via Contrastive Pretrained Large Language Model

open access: yesAdvanced Science, EarlyView.
In this work, CoSP (contrastive multi‐state pretrain), an intelligent inverse design method for reconfigurable metamaterials based on a contrastive pretrained large language model, is proposed. Numerical experiments demonstrate that CoSP can design reconfigurable metamaterial structures for multi‐state, multi‐band optical responses, showing great ...
Shujie Yang   +4 more
wiley   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

Toward High‐Resolution Polymeric Neural Interfaces: A Practical Guide for Electron Beam Lithography

open access: yesAdvanced Science, EarlyView.
Electron beam lithography (EBL) enables sub‐micron patterning of polymer‐based neural implants, overcoming the resolution limits of optical lithography. By addressing challenges such as charging, non‐planarity, and substrate heating, it supports higher channel density, improved miniaturization, and better long‐term tissue integration.
Hanna Karlsson‐Fernberg, Maria Asplund
wiley   +1 more source

Error bounds for decode-and-forward relaying

open access: yes, 2010
International audienceWe analyze and compare the maximum-likelihood (ML) decoder and the maximum a-posteriori (MAP) decoder for coding over a decode-and-forward relay network with orthogonal channels.
Land, Ingmar   +2 more
core   +2 more sources

Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation

open access: yesAdvanced Science, EarlyView.
A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley   +1 more source

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