Results 161 to 170 of about 1,331 (215)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen   +8 more
wiley   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

open access: yesAdvanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong   +6 more
wiley   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu   +11 more
wiley   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

open access: yesAdvanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song   +8 more
wiley   +1 more source

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

open access: yesAdvanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma   +8 more
wiley   +1 more source

Hierarchical Physical‐Cyber Encryption via Metasurface‐Encoded Holographic Keys

open access: yesAdvanced Science, EarlyView.
ABSTRACT Physical‐layer encryption based on metasurfaces has emerged as a promising alternative to conventional algorithmic cryptography by embedding security into physical processes. However, most existing metasurface‐based encryption schemes operate within single‐stage or static frameworks, where correct physical illumination directly reveals the ...
Zhen Liu   +8 more
wiley   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

open access: yesAdvanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang   +11 more
wiley   +1 more source

Energy of decoding algorithms

2013 13th Canadian Workshop on Information Theory, 2013
A standard model for the energy of a computation was developed by Thompson, which relates the energy of a computation to the product of the area a circuit and the number of clock cycles needed to carry out the computation. We show that for any circuit implemented this way, using any algorithm that performs decoding of a codeword passed through a binary
Christopher Blake, Frank R. Kschischang
openaire   +1 more source

On robust decoding algorithm

1999 IEEE International Conference on Communications (Cat. No. 99CH36311), 2003
We study and develop several robust decoding algorithms based on the minimax rule. The algorithms robust to estimation errors and channel variations. The decoding problem is studied when using a matched and mismatched decoder. Examples using robust the Viterbi algorithm (1967) and MAP algorithm are also presented.
Zheng Li   +3 more
openaire   +1 more source

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