Factors associated with spontaneous clearance of chronic hepatitis C virus infection [PDF]
, 2016 Background & Aims: Spontaneous clearance of chronic hepatitis C virus (HCV) infection (CHC) is rare. We conducted a retrospective case-control study to identify rates and factors associated with spontaneous clearance of CHC.
Aitken, Celia +11 more
core +2 more sources
Machine Learning-Based Prediction of Decompensation in Hepatitis B Virus-Related Cirrhosis
DiagnosticsBackground/Objectives: Fatality of cirrhotic patients greatly increases when they progress to the decompensated state. Only a few studies to date have applied machine learning (ML) methods to predict decompensation in cirrhosis patients.
Hsueh-Chun Lin +6 more
doaj +1 more source
Hepatic decompensation associated with an interferon-free antiviral therapy in patients with HCV-cirrhosis [PDF]
Терапевтический архив, 2018 Today, there is no complete clarity about the pathogenetic mechanisms of the hepatic decompensation in patients with HCV-cirrhosis during the course of direct-acting antiviral (DAAs) therapy. The current article describes several clinical observations of
S N Batskikh +3 more
doaj +1 more source
Journal of Cardiovascular Development and Disease, 2023 Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Heart failure (HF) occurs when the heart is not able to pump enough blood to satisfy metabolic needs.
Jon Kerexeta +6 more
doaj +1 more source
Hepatic Glycogen Storage Diseases in Brazil: A Multicenter Study
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT To describe clinical and laboratory characteristics, emphasizing the evolution of patients with hepatic glycogen storage diseases (GSDs) followed in Brazilian reference centers. Multicenter, retrospective study involving 13 centers, using RedCap platform. 132 patients were included: 63 (47.8%) GSD type I (56 Ia, 7 Ib), 13 (9.8%) with type III (
Mariana Pena Costa +23 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]
, 2018 It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P +5 more
core +1 more source
DECOMPENSATED CIRRHOSIS; PREVALENCE OF GASTRIC VARICES
The Professional Medical Journal, 2015 Cirrhosis with subsequent portal hypertension is a major health problemworldwide. Among various etiologies, HCV is the leading cause of chronic hepatocellularinjury. Cirrhosis being the commonest cause of portal hypertension results in a spectrum ofcomplications. Approximately 5-15% of cirrhotic develop varices.
Sarwat Iqbal +3 more
openaire +2 more sources
Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier +2 more
wiley +1 more source
Compensated right ventricular function of the onset of pulmonary hypertension in a rat model depends on chamber remodeling and contractile augmentation. [PDF]
, 2018 Right-ventricular function is a good indicator of pulmonary arterial hypertension (PAH) prognosis; however, how the right ventricle (RV) adapts to the pressure overload is not well understood.
Abe K +35 more
core +1 more source